Carpal tunnel syndrome laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Dheeraj Makkar, M.D.[2]

• Nonspecific:

No direct laboratory marker confirms CTS.

• Supportive / Etiologic evaluation:

• • Thyroid function tests: Hypothyroidism is a known risk factor.

• • Fasting glucose / HbA1c: To evaluate for diabetes mellitus, which is associated with peripheral neuropathy and CTS.

• • Vitamin B12 levels: To rule out concomitant neuropathy.

• • Rheumatologic markers (ESR, CRP, ANA, RF): May be obtained if inflammatory arthritis (e.g., rheumatoid arthritis, lupus) is suspected.

• • Uric acid: Considered in suspected gout-related CTS.