Caroverine

Caroverine

Clinical data
Routes of administration	Oral
ATC code	A03AX11 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 1-[2-(diethylamino)ethyl]- 3-(4-methoxybenzyl)quinoxalin- 2(1H)-one
CAS Number	23465-76-1 Y
PubChem CID	65709
ChemSpider	59135 Y
UNII	XJ73B0K6KB
ChEMBL	ChEMBL1729803 N
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C22H27N3O2
Molar mass	365.47 g/mol
3D model (JSmol)	Interactive image
SMILES O=C/1N(c3c(\N=C\1Cc2ccc(OC)cc2)cccc3)CCN(CC)CC
InChI InChI=1S/C22H27N3O2/c1-4-24(5-2)14-15-25-21-9-7-6-8-19(21)23-20(22(25)26)16-17-10-12-18(27-3)13-11-17/h6-13H,4-5,14-16H2,1-3H3 Y Key:MSPRUJDUTKRMLM-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

WikiDoc Resources for Caroverine
Articles
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Evidence Based Medicine
Cochrane Collaboration on Caroverine Bandolier on Caroverine TRIP on Caroverine
Clinical Trials
Ongoing Trials on Caroverine at Clinical Trials.gov Trial results on Caroverine Clinical Trials on Caroverine at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Caroverine NICE Guidance on Caroverine NHS PRODIGY Guidance FDA on Caroverine CDC on Caroverine
Books
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News
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Commentary
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Definitions
Definitions of Caroverine
Patient Resources / Community
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Healthcare Provider Resources
Symptoms of Caroverine Causes & Risk Factors for Caroverine Diagnostic studies for Caroverine Treatment of Caroverine
Continuing Medical Education (CME)
CME Programs on Caroverine
International
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Business
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Experimental / Informatics
List of terms related to Caroverine

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Caroverine (Spasmium, Spadon, Tinnex) is a drug used as a spasmolytic and otoneuroprotective (inner ear protective) agent in some countries. It acts as an N-type calcium channel blocker, competitive AMPA receptor antagonist, and non-competitive NMDA receptor antagonist. It also has potent antioxidant effects.

Applications

Caroverine has been demonstrated to have a high rate of efficacy in the treatment of cochlear-synaptic tinnitus.