CD3EAP

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External IDs	GeneCards: [1]
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	Wikidata
View/Edit Human

DNA-directed RNA polymerase I subunit RPA34 is an enzyme that in humans is encoded by the CD3EAP gene.^[1]^[2]^[3]^[4]

Interactions

CD3EAP has been shown to interact with T-cell surface glycoprotein CD3 epsilon chain,^[1] POLR1E^[3] and POLR1C.^[3]

References

↑ ^1.0 ^1.1 Yamazaki T, Hamano Y, Tashiro H, Itoh K, Nakano H, Miyatake S, Saito T (Jul 1999). "CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells". J Biol Chem. 274 (26): 18173–80. doi:10.1074/jbc.274.26.18173. PMID 10373416.
↑ Whitehead CM, Winkfein RJ, Fritzler MJ, Rattner JB (Mar 1998). "ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes". Chromosoma. 106 (8): 493–502. doi:10.1007/s004120050271. PMID 9426281.
↑ ^3.0 ^3.1 ^3.2 Yamamoto K, Yamamoto M, Hanada K, Nogi Y, Matsuyama T, Muramatsu M (Jun 2004). "Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription". Mol Cell Biol. 24 (14): 6338–49. doi:10.1128/MCB.24.14.6338-6349.2004. PMC 434256. PMID 15226435.
↑ "Entrez Gene: CD3EAP CD3e molecule, epsilon associated protein".

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ma J, Dempsey AA, Stamatiou D, et al. (2007). "Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects". Atherosclerosis. 191 (1): 63–72. doi:10.1016/j.atherosclerosis.2006.05.032. PMID 16806233.
Panov KI, Panova TB, Gadal O, et al. (2006). "RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor". Mol. Cell. Biol. 26 (14): 5436–48. doi:10.1128/MCB.00230-06. PMC 1592716. PMID 16809778.
Skjelbred CF, Saebø M, Nexø BA, et al. (2006). "Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study". BMC Cancer. 6: 175. doi:10.1186/1471-2407-6-175. PMC 1533843. PMID 16817948.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.

External links

Human CAST genome location and CAST gene details page in the UCSC Genome Browser.
Human CD3EAP genome location and CD3EAP gene details page in the UCSC Genome Browser.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

[pmid10373416-1] 1.0 ^1.1 Yamazaki T, Hamano Y, Tashiro H, Itoh K, Nakano H, Miyatake S, Saito T (Jul 1999). "CAST, a novel CD3epsilon-binding protein transducing activation signal for interleukin-2 production in T cells". J Biol Chem. 274 (26): 18173–80. doi:10.1074/jbc.274.26.18173. PMID 10373416.

[pmid9426281-2] Whitehead CM, Winkfein RJ, Fritzler MJ, Rattner JB (Mar 1998). "ASE-1: a novel protein of the fibrillar centres of the nucleolus and nucleolus organizer region of mitotic chromosomes". Chromosoma. 106 (8): 493–502. doi:10.1007/s004120050271. PMID 9426281.

[pmid15226435-3] 3.0 ^3.1 ^3.2 Yamamoto K, Yamamoto M, Hanada K, Nogi Y, Matsuyama T, Muramatsu M (Jun 2004). "Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription". Mol Cell Biol. 24 (14): 6338–49. doi:10.1128/MCB.24.14.6338-6349.2004. PMC 434256. PMID 15226435.

[entrez-4] "Entrez Gene: CD3EAP CD3e molecule, epsilon associated protein".

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CD3EAP

Contents

Interactions

References

Further reading

External links

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