C4 glomerulopathy laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Ali Poyan Mehr, M.D. [2]; Associate Editor(s)-in-Chief: Olufunmilola Olubukola M.D.[3]

Overview

Laboratory findings consistent with the diagnosis of C4 glomerulopathy include abnormal urinalysis, abnormal BUN: Creatinine ratio, and abnormal serum C3 and C4 levels.

Laboratory Findings

Laboratory findings consistent with the diagnosis of C4 glomerulopathy include[1]:

  • Abnormal urinalysis: proteinuria, hematuria
  • Abnormal BUN: Creatinine ratio
  • Abnormal urine protein creatinine ratio
  • Abnormal serum albumin and creatinine
  • Positive serum C4 and C3 levels

References

  1. Chandra P (2019). "C4d in Native Glomerular Diseases". Am J Nephrol. 49 (1): 81–92. doi:10.1159/000496059. PMID 30612132.

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