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Butylscopolamine Wiki Str.png
Clinical data
Routes of
Oral, rectal, intravenous
ATC code
Legal status
Legal status
Pharmacokinetic data
Protein bindingLow
Elimination half-life5 hours
ExcretionRenal (50%) and fecal
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
Molar mass360.467 g/mol

Butylscopolamine, also known as scopolamine butylbromide and hyoscine butylbromide is an abdominal-specific antispasmodic. It is marketed under the trade name Buscopan by Boehringer Ingelheim GmbH, Germany, who also offer a combination of butylscopolamine and acetaminophen, marketed under the name Buscopan Plus.

Butylscopolamine is used to treat pain and discomfort caused by abdominal cramps or other spasmodic activity in the digestive system. When taken orally, it cannot enter the bloodstream or otherwise leave the digestive tract, so that it is only able to affect the smooth muscles of the digestive system as it passes through. It is not an analgesic in the normal sense, since it doesn't 'mask' or 'cover over' the pain, but rather works to prevent painful cramps and spasms from occurring in the first place.


Butylscopolamine is often prescribed at a low dosage, commonly 10mg three times a day, as a means of managing some of the symptoms of Irritable bowel syndrome.

External links

Template:Drugs for functional gastrointestinal disorders