Diffuse pain

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Aches; chronic pain; musculoskeletal pain

Causes

Common Causes

• Chronic fatigue syndrome
• Fibromyalgia
• Mood disorder
• Myositis
• Neuropathies
• Polymyalgia rheumatica
• Systemic lupus erythematosus
• Bilateral soft tissue rheumatism

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	No underlying causes
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	Statins
Ear Nose Throat	No underlying causes
Endocrine	Hypothyroidism, Hyperthyroidism, Hyperparathyroidism, Adrenal insufficiency
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	No underlying causes
Hematologic	Eosinophilia-myalgia syndrome
Iatrogenic	No underlying causes
Infectious Disease	Viral infection, Spirochetal infection, Bacterial infection
Musculoskeletal/Orthopedic	Paget’s disease, Osteomalacia, Myositis, Myofascial pain syndrome, Muscle soreness from overuse, Chronic fatigue syndrome
Neurologic	Entrapment neuropathy, Neuropathies, Multiple Sclerosis
Nutritional/Metabolic	Scurvy , Metabolic myopathy
Obstetric/Gynecologic	No underlying causes
Oncologic	Paraneoplastic syndrome
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	Psycogenic rheumatism, Mood disorder, Depressed affect
Pulmonary	No underlying causes
Renal/Electrolyte	Hypophosphatemia
Rheumatology/Immunology/Allergy	Vasculitis, Systemic lupus erythematosus, Spondyloarthropathy, Sjogren syndrome, Rheumatoid Arthritis, Reiter's Syndrome, Polymyalgia rheumatica, Fibromyalgia, Dermatomyositis, Dermatomyositis, Chronic fatigue syndrome , Bilateral soft tissue rheumatism, Postviral arthralgia, Ankylosing Spondylitis
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	Overuse Syndromes, Hypermobility

Causes in Alphabetical Order

• Adrenal insufficiency
• Ankylosing Spondylitis
• Postviral arthralgia
• Bacterial infection
• Bilateral soft tissue rheumatism
• Body-wide infection
• Chronic fatigue syndrome
• Depressed affect
• Dermatomyositis
• Dermatomyositis
• Eosinophilia-myalgia syndrome
• Fibromyalgia
• Hypermobility
• Hyperparathyroidism

• Hyperthyroidism
• Hypophosphatemia
• Hypothyroidism
• Metabolic myopathy
• Mood disorder
• Multiple Sclerosis
• Muscle soreness from overuse
• Myofascial pain syndrome
• Myositis
• Neuropathic
• Entrapment neuropathy
• Overuse Syndromes
• Osteomalacia
• Paget disease

• Paraneoplastic syndrome
• Polymyalgia rheumatica
• Psycogenic rheumatism
• Reiter's Syndrome
• Rheumatoid Arthritis
• Scurvy
• Sjogren syndrome
• Spirochetal infection
• Spondyloarthropathy
• statins
• Systemic lupus erythematosus
• Vasculitis
• Viral infection