Autoimmune lymphoproliferative syndrome other imaging findings

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Autoimmune lymphoproliferative syndrome Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sharmi Biswas, M.B.B.S

Overview

Fluorodeoxyglucose positron emission tomography (FDG-PET) may be helpful in the diagnosis of Autoimmune lymphoproliferative syndrome(ALPS) by distinguishing benign lymphadenopathy from malignant lymphadenopathy.

Other Imaging Findings

PET scan can be an useful tool to minimize the number of lymph nodes to get biopsied based on degree of FDG acitivity in ALPS pateints with lymphoma.FDG distribution in ALPS might be helpful to distiguish between ALPS adenopathy and ALPS associated lymphoma. [1]

CT and FDG-PET scans featuring ALPS-FAS–associated lymphadenopathy and splenomegaly.[1]

References

  1. 1.0 1.1 Rao, V. Koneti; Oliveira, João Bosco (2011). "How I treat autoimmune lymphoproliferative syndrome". Blood. 118 (22): 5741–5751. doi:10.1182/blood-2011-07-325217. ISSN 0006-4971.