Asherman's syndrome risk factors

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Editor(s)-in-Chief: Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Canan S Fornusek, Ph.D.; Associate Editor-In-Chief: Saud Khan M.D.


The strongest risk factors for developing Asherman Syndrome is previous obstetric curettage procedures and infections.

Risk Factors

The risk of Asherman's increases with the number of procedures: one study estimated the risk to be 16% after one D&C and 32% after 3 or more D&Cs [1]. Other risk factors may include

Women may be predisposed to intrauterine adhesions if they are of increased age, poor nutritional status during pregnancy, and have experienced intrauterine or genital infectious processes. However, such factors are not supported in the literature, where the dominant factor seems to be surgical trauma (frequent hysteroscopic surgery, repeat curettages and infection).[2]


  1. Friedler S, Margalioth EJ, Kafka I, Yaffe H. (1993). "Incidence of postabortion intra-uterine adhesions evaluated by hysteroscopy: a prospective study". Hum Reprod. 8 (3): 442–444. PMID 8473464. Text "doi" ignored (help)
  2. Di Spiezio Sardo A, Calagna G, Scognamiglio M, O'Donovan P, Campo R, De Wilde RL (2016). "Prevention of intrauterine post-surgical adhesions in hysteroscopy. A systematic review". Eur J Obstet Gynecol Reprod Biol. 203: 182–92. doi:10.1016/j.ejogrb.2016.05.050. PMID 27337414.

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