Antrafenine
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| File:Antrafenine.png | |
| Gene therapy | |
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| Clinical data | |
| Routes of administration | oral |
| Physiological data | |
| Legal status | |
| Pharmacokinetic data | |
| Metabolism | hepatic |
| Excretion | renal |
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| CAS Number | |
| PubChem Template:Abbreviation | |
| Chemical and physical data | |
| Formula | C30H26F6N4O2 |
| Molar mass | 588.543 g/mol |
Antrafenine (Stakane) is a piperazine derivative drug invented in 1979. [1] It acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen,[2] but is not widely used as it has largely been replaced by newer drugs.
References
- ↑ Manoury PM, Dumas AP, Najer H, Branceni D, Prouteau M, Lefevre-Borg FM. Synthesis and analgesic activities of some (4-substituted phenyl-1-piperazinyl)alkyl 2-aminobenzoates and 2-aminonicotinates. Journal of Medicinal Chemistry. 1979 May;22(5):554-9.
- ↑ Leatham PA, Bird HA, Wright V, Seymour D, Gordon A. A double blind study of antrafenine, naproxen and placebo in osteoarthrosis. European Journal of Rheumatology and Inflammation. 1983;6(2):209-11.
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- Piperazines