Aglepristone

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Aglepristone
Clinical data
ATC code	G03XB90 (WHO) ;
Identifiers
	IUPAC name (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-[(1Z)-1-propen-1-yl]estra-4,9-dien-3-one;
CAS Number	124478-60-0;
PubChem CID	14153279;
ChemSpider	16736563;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C29H37NO2
Molar mass	431.610 g/mol
3D model (JSmol)	Interactive image;
	SMILES C/C=C\[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)c5ccc(cc5)N(C)C)C)O;
	InChI InChI=1S/C29H37NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h5-7,9-10,15,17,24-26,32H,8,11-14,16,18H2,1-4H3/b15-5-/t24-,25+,26-,28-,29-/m0/s1; Key:RTCKAOKDXNYXEH-FWSJOHTJSA-N;

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Aglepristone (INN) (brand name Alizine; former code names RU-46534, RU-534) is a steroidal antiprogestin (progesterone receptor full antagonist) related to mifepristone which is marketed by Virbac in several European countries for use in veterinary medicine.^[1]^[2]^[3] It is specifically used as an abortifacient in pregnant.^[1]^[3]^[4] Aglepristone, similarly to mifepristone, also possesses some antiglucocorticoid activity.^{[citation needed]}

References

↑ ^1.0 ^1.1 John D. Bonagura; David C. Twedt (1 December 2013). Kirk's Current Veterinary Therapy XV. Elsevier Health Sciences. pp. 3009–. ISBN 978-0-323-22762-9.
↑ E. James Squires (2010). Applied Animal Endocrinology. CABI. pp. 207–. ISBN 978-1-84593-755-3.
↑ ^3.0 ^3.1 Mark G. Papich (3 November 2010). Saunders Handbook of Veterinary Drugs: Small and Large Animal. Elsevier Health Sciences. pp. 120–. ISBN 1-4377-0192-2.
↑ Patrick W. Concannon (2001). Advances in reproduction in dogs, cats and exotic carnivores: proceedings of the fourth International Symposium on Canine and Feline Reproduction, Oslo, Norway, 29 June-1 July 2000. Journal of Reproduction and Fertility. ISBN 978-0-906545-37-9.

[BonaguraTwedt2013-1] 1.0 ^1.1 John D. Bonagura; David C. Twedt (1 December 2013). Kirk's Current Veterinary Therapy XV. Elsevier Health Sciences. pp. 3009–. ISBN 978-0-323-22762-9.

[Squires2010-2] E. James Squires (2010). Applied Animal Endocrinology. CABI. pp. 207–. ISBN 978-1-84593-755-3.

[Papich2010-3] 3.0 ^3.1 Mark G. Papich (3 November 2010). Saunders Handbook of Veterinary Drugs: Small and Large Animal. Elsevier Health Sciences. pp. 120–. ISBN 1-4377-0192-2.

[Concannon2001-4] Patrick W. Concannon (2001). Advances in reproduction in dogs, cats and exotic carnivores: proceedings of the fourth International Symposium on Canine and Feline Reproduction, Oslo, Norway, 29 June-1 July 2000. Journal of Reproduction and Fertility. ISBN 978-0-906545-37-9.

[1]

[2]

[3]

[4]

Clinical data

ATC code	G03XB90 (WHO)
Identifiers
IUPAC name (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-[(1Z)-1-propen-1-yl]estra-4,9-dien-3-one
CAS Number	124478-60-0
PubChem CID	14153279
ChemSpider	16736563
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₂₉H₃₇NO₂
Molar mass	431.610 g/mol
3D model (JSmol)	Interactive image
SMILES C/C=C\[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)c5ccc(cc5)N(C)C)C)O
InChI InChI=1S/C29H37NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h5-7,9-10,15,17,24-26,32H,8,11-14,16,18H2,1-4H3/b15-5-/t24-,25+,26-,28-,29-/m0/s1 Key:RTCKAOKDXNYXEH-FWSJOHTJSA-N

Aglepristone

Overview

References

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