4-HO-DBT

4-HO-DBT

File:4-HO-DBT.svg
Gene therapy
Clinical data
Physiological data
Legal status
Pharmacokinetic data
Identifiers
IUPAC name N-butyl-N-[2-(4-hydroxy-1H-indol-3-yl)ethyl]butan-1-amine
Chemical and physical data
Formula	C18H28N2O
Molar mass	288.44 g/mol
Melting point	74 to 75 °C

4-Hydroxydibutyltryptamine (4-HO-DBT) is a psychedelic drug belonging to the tryptamine family. It is found either as its crystalline hydrochloride salt or as an oily or crystalline base. 4-HO-DBT was first made by the chemist Alexander Shulgin and reported in his book TiHKAL. Shulgin reported a dosage of 20mg orally to be without effects. However this compound has subsequently been sold as a "research chemical" and anecdotal reports suggest that at higher doses 4-HO-DBT is indeed an active hallucinogen, although somewhat weaker than other similar tryptamine derivatives.

Several different isomers of this compound could potentially be made (see DBT for a fuller discussion) but of these only the isobutyl isomer 4-HO-DIBT has been synthesised (mp 152-154 °C) and was also found to be inactive at a 20mg dose.

External link

• TiHKAL entry