Transitional cell carcinoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Among transitional cell carcinomas, upper urinary tract transitional cell carcinomas are rare cancers accounting for 5-7% of all transitional cell cancer cases.

Epidemiology and Demographics

  • Transitional cell carcinomas of upper urinary tract are rare cancers accounting for 5-7% of all transitional cell cancer cases.[1]
  • Transitional cell carcinoma of the renal pelvis, accounts for only 7% of all kidney tumors.[2]
  • Transitional cell cancer of the ureter, accounts for only 1 of every 25 upper tract tumors.

Incidence

  • The incidence of upper urinary tract transitional cell carcinoma was estimated to be 0.6-1.1 cases per 100,000 individuals in the United States.[1]

Age

  • Transitional cell carcinoma commonly affects individuals older than 60 years of age with the average age of presentation being 65.
  • Transitional cell carcinoma of the urinary bladder is rare in young adults, as less than 1% of such tumors present in the first 4 decades of life.[3]

Gender

  • Males are more commonly affected with transitional cell carcinoma than females. The male to female ratio is approximately 2 to 1.

References

  1. 1.0 1.1 Kirkali, Ziya; Tuzel, Emre (2003). "Transitional cell carcinoma of the ureter and renal pelvis". Critical Reviews in Oncology/Hematology. 47 (2): 155–169. doi:10.1016/S1040-8428(03)00079-9. ISSN 1040-8428.
  2. Transitional cell cancer. National cancer institute. http://www.cancer.gov/types/kidney/hp/transitional-cell-treatment-pdq#section/_1
  3. Nomikos, Michael; Pappas, Athanasios; Kopaka, Maria-Emmanouela; Tzoulakis, Stavros; Volonakis, Ioannis; Stavrakakis, Georgios; Avgenakis, Georgios; Anezinis, Ploutarchos (2011). "Urothelial Carcinoma of the Urinary Bladder in Young Adults: Presentation, Clinical behavior and Outcome". Advances in Urology. 2011: 1–4. doi:10.1155/2011/480738. ISSN 1687-6369.

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