Spontaneous coronary artery dissection risk factors: Difference between revisions
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* '''[[Drugs]]:''' [[Calcineurin|calcineurin inhibitors]], [[5-FU]], [[fenfluramine]], [[corticosteroids]], [[methylphenidate]], [[ergotamine]], [[sumatriptan]], [[hypersensitivity reactions]], [[dobutamine]] | * '''[[Drugs]]:''' [[Calcineurin|calcineurin inhibitors]], [[5-FU]], [[fenfluramine]], [[corticosteroids]], [[methylphenidate]], [[ergotamine]], [[sumatriptan]], [[hypersensitivity reactions]], [[dobutamine]] | ||
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'''Features that raise the index of suspicion for [[SCAD]] include:'''<ref name="pmid24227590">{{cite journal| author=Saw J| title=Coronary angiogram classification of spontaneous coronary artery dissection. | journal=Catheter Cardiovasc Interv | year= 2014 | volume= 84 | issue= 7 | pages= 1115-22 | pmid=24227590 | doi=10.1002/ccd.25293 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24227590 }}</ref> | |||
* [[Myocardial infarction]] in young women (age ≤50) | |||
* Absence of traditional [[Cardiovascular disease#Risk factors|cardiovascular risk factors]] | |||
* Little or no evidence of [[coronary atherosclerosis]] | |||
* [[Peripartum|Peripartum state]] | |||
* History of [[fibromuscular dysplasia]] | |||
* History of [[connective tissue disorder]] or [[systemic inflammation|systemic inflammatory disorder]]: | |||
:* [[Marfan's syndrome]] | |||
:* [[Ehlers-Danlos syndrome|Type 4 Ehlers-Danlos syndrome]] | |||
:* [[Loeys-Dietz syndrome]] | |||
:* [[Cystic medial necrosis]] | |||
:* [[Systemic lupus erythematosus]] | |||
:* [[Crohn's disease]] | |||
:* [[Ulcerative colitis]] | |||
:* [[Polyarteritis nodosa]] | |||
:* [[Sarcoidosis]] | |||
:* [[Churg-Strauss syndrome]] | |||
:* [[Wegener's granulomatosis]] | |||
:* [[Rheumatoid arthritis]] | |||
:* [[Giant cell arteritis]] | |||
==References== | ==References== | ||
Revision as of 07:03, 4 March 2021
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Spontaneous Coronary Artery Dissection Microchapters |
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Differentiating Spontaneous coronary artery dissection from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Type 1 Type 2A Type 2B Type 3 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A. Arzu Kalayci, M.D. [2]
Synonyms and keywords: SCAD
Overview
The risk factors for spontaneous coronary artery dissection include predisposing factors (e.g., vasculopathy, pregnancy, connective tissue disorder, systemic inflammation) and precipitating stressors (e.g., strenuous exercise, emotional stress, recreational drugs).
Risk Factors
- The phenotypic manifestation of spontaneous coronary artery dissection (SCAD) may occur as a result of predisposing factors compounded by precipitating stressors.[1] *The presence of either predisposing or precipitating factors increases the risk of developing a dissection.
- The potential risk factors for SCAD include:[2][3]
Features that raise the index of suspicion for SCAD include:[4]
- Myocardial infarction in young women (age ≤50)
- Absence of traditional cardiovascular risk factors
- Little or no evidence of coronary atherosclerosis
- Peripartum state
- History of fibromuscular dysplasia
- History of connective tissue disorder or systemic inflammatory disorder:
References
- ↑ Saw, Jacqueline; Mancini, G.B. John; Humphries, Karin H. (2016). "Contemporary Review on Spontaneous Coronary Artery Dissection". Journal of the American College of Cardiology. 68 (3): 297–312. doi:10.1016/j.jacc.2016.05.034. ISSN 0735-1097.
- ↑ Saw, J.; Aymong, E.; Sedlak, T.; Buller, C. E.; Starovoytov, A.; Ricci, D.; Robinson, S.; Vuurmans, T.; Gao, M.; Humphries, K.; Mancini, G. B. J. (2014). "Spontaneous Coronary Artery Dissection: Association With Predisposing Arteriopathies and Precipitating Stressors and Cardiovascular Outcomes". Circulation: Cardiovascular Interventions. 7 (5): 645–655. doi:10.1161/CIRCINTERVENTIONS.114.001760. ISSN 1941-7640.
- ↑ Adlam, David; Alfonso, Fernando; Maas, Angela; Vrints, Christiaan; al-Hussaini, Abtehale; Bueno, Hector; Capranzano, Piera; Gevaert, Sofie; Hoole, Stephen P; Johnson, Tom; Lettieri, Corrado; Maeder, Micha T; Motreff, Pascal; Ong, Peter; Persu, Alexandre; Rickli, Hans; Schiele, Francois; Sheppard, Mary N; Swahn, Eva (2018). "European Society of Cardiology, acute cardiovascular care association, SCAD study group: a position paper on spontaneous coronary artery dissection". European Heart Journal. doi:10.1093/eurheartj/ehy080. ISSN 0195-668X.
- ↑ Saw J (2014). "Coronary angiogram classification of spontaneous coronary artery dissection". Catheter Cardiovasc Interv. 84 (7): 1115–22. doi:10.1002/ccd.25293. PMID 24227590.