Sarcoidosis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Roshan Dinparasti Saleh M.D.
Overview
History and Symptoms
Pulmonary Sarcoidosis
- Sarcoidosis commonly involves patients between 20 and 60 years of age[1]. Lung is the most common organ involved by sarcoidosis, but up to 30% of patients present with extrapulmonary sarcoidosis[2][3]. Pulmonary sarcoidosis commonly presents with cough, dyspnea, chest pain, and infrequently fatigue, malaise, fever, and weight loss[4].
- Young children can present with skin rash, arthritis, uveitis, and erythema nodosum, without a predominant lung involvement[5][6]
Cutaneous Sarcoidosis
in 25% of the patients diagnosed with sarcoidosis, cutaneous involvement is seen[7]. The most common patterns of involvement is: papular, nodular, plaque-like, lupus pernio, erythema nodosum, subcutaneous sarcoidosis. See cutaneous manifestations of sarcoidosis in physical exam for more detail.
References
- ↑ Judson MA, Boan AD, Lackland DT: The clinical course of sarcoidosis: presentation, diagnosis, and treatment in a large white and black cohort in the United States. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 2012, 29(2):119-127.
- ↑ Ungprasert P, Carmona EM, Utz JP, Ryu JH, Crowson CS, Matteson EL: Epidemiology of Sarcoidosis 1946-2013: A Population-Based Study. Mayo Clinic proceedings 2016, 91(2):183-188.
- ↑ Baughman RP, Teirstein AS, Judson MA, Rossman MD, Yeager H, Jr., Bresnitz EA, DePalo L, Hunninghake G, Iannuzzi MC, Johns CJ et al: Clinical characteristics of patients in a case control study of sarcoidosis. American journal of respiratory and critical care medicine 2001, 164(10 Pt 1):1885-1889.
- ↑ Sharma OP: Fatigue and sarcoidosis. The European respiratory journal 1999, 13(4):713-714.
- ↑ Pattishall EN, Kendig EL, Jr.: Sarcoidosis in children. Pediatric pulmonology 1996, 22(3):195-203.
- ↑ Milman N, Hoffmann AL: Childhood sarcoidosis: long-term follow-up. The European respiratory journal 2008, 31(3):592-598.
- ↑ Roberts SD, Mirowski GW, Wilkes D, Kwo PY, Knox KS: Sarcoidosis. Part II: extrapulmonary and systemic manifestations. Journal of the American Academy of Dermatology 2004, 51(4):628-630.