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==Overview==
==Overview==
In virtually all cases, Rocky Mountain spotted fever presents with a [[rash]]. When trying to differentiate RMSF with other infections, it should be noted that there has been a rare case in which RMSF has presented without the typical rash.
In virtually all cases, Rocky Mountain spotted fever presents with a [[rash]]. When trying to differentiate RMSF with other infections, it should be noted that there has been a rare case in which RMSF has presented without the typical rash.
==Differential Diagnosis==


==Case Study==
==Case Study==

Revision as of 22:59, 13 July 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Michael Maddaleni, B.S. João André Alves Silva, M.D. [2]

Overview

In virtually all cases, Rocky Mountain spotted fever presents with a rash. When trying to differentiate RMSF with other infections, it should be noted that there has been a rare case in which RMSF has presented without the typical rash.

Differential Diagnosis

Case Study

A crucial piece of the Rocky Mountain spotted fever puzzle has to do with making an early diagnosis, which can prove very difficult at times. It can be especially difficult when a patient doesn't present with the symptoms normally associated with the specific infection. A rare symptom of RMSF is severe rhabdomyolysis in which all of the known cases present with an accompanying rash[1]. There was an unusual case that presented a young male who has severe rhabdomyolysis without an accompanying rash.

Presentation of 16 year old male[1].

  • Hospitalized for 4 days with high fever
  • Gastrointestinal symptoms for 2 days
  • Severe pain in lower extremities
  • Walking became difficult
  • No history of
    • Tick bite
    • Travel
    • Sick contact
  • No rash but extreme tenderness in both thighs
  • Motor testing was limited (due to pain)
  • Neurological testing was normal

Laboratory findings[1].

Conclusion[1].

  • Doxycycline was the treatment of choice for 10 days
  • Patient was afebrile after 3 days
  • Patient began walking after a week
  • RMSF should be considered as a possible diagnosis even if a rash is not present. It can be considered a rare cause of severe rhabdomyolysis after common causes have been sufficiently ruled out.

References

  1. 1.0 1.1 1.2 1.3 Moudigoudar, B. Arya, K. Jalandoni, K. McSween, T. (2011). Unusual presentation of Rocky Mountain spotted fever. Annals of Neurology. Volume 70(S15), S167-S168.