Difference between revisions of "Riedel's thyroiditis"

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  DiseasesDB    = 11590 |
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  ICD10          = {{ICD10|E|06|5|e|00}} |
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  ICD9          = {{ICD9|245.3}} |
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  eMedicineSubj  = med |
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  eMedicineTopic = 2036 |
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'''Riedel's thyroiditis''', also called '''Riedel's struma''' is a chronic form of [[thyroiditis]].
  
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==Pathophysiology==
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Riedel's thyroiditis is characterized by a replacement of the normal thyroid parenchyma by a dense [[fibrosis]] that invades adjacent structures of the neck and extends beyond the thyroid capsule.<ref name="pmid17603227">{{cite journal |author=Cho MH, Kim CS, Park JS, ''et al'' |title=Riedel's thyroiditis in a patient with recurrent subacute thyroiditis: a case report and review of the literature |journal=Endocr. J. |volume=54 |issue=4 |pages=559–62 |year=2007 |month=August |pmid=17603227 |doi= |url=http://joi.jlc.jst.go.jp/JST.JSTAGE/endocrj/K06-186?from=PubMed}}</ref> This makes the thyroid gland stone-hard and fixed to adjacent structures.
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A shared mechanism with [[retroperitoneal fibrosis]] and [[sclerosing cholangitis]] has been suggested.<ref name="pmid8504980">{{cite journal |author=De Boer WA |title=Riedel's thyroiditis, retroperitoneal fibrosis, and sclerosing cholangitis: diseases with one pathogenesis? |journal=Gut |volume=34 |issue=5 |pages=714 |year=1993 |month=May |pmid=8504980 |pmc=1374200 |doi= |url=http://gut.bmj.com/cgi/pmidlookup?view=long&pmid=8504980}}</ref>
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==Prevalence==
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Riedel's thyroiditis is classified as rare.  Most patients remain euthyroid, but approximately 30% of patients become hypothyroid and very few patients are hyperthyroid.  It is most seen in women.<ref name=emedicine>[http://www.emedicine.com/med/topic2036.htm eMedicine]</ref>
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==Treatment==
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[[Tamoxifen]] has been proposed as part of a treatment plan.<ref name="pmid12698518">{{cite journal |author=Dabelic N, Jukic T, Labar Z, Novosel SA, Matesa N, Kusic Z |title=Riedel's thyroiditis treated with tamoxifen |journal=Croat. Med. J. |volume=44 |issue=2 |pages=239–41 |year=2003 |month=April |pmid=12698518 |doi= |url=http://www.cmj.hr/2003/44/2/12698518.pdf|format=PDF}}</ref>
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==Eponym==
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It is named for Bernhard Riedel. He first recognized the disease In 1883 and  published its description in 1896.<ref>B. M. C. L. Riedel. Die chronische, zur Bildung eisenharter Tumoren führende Entzündung der Schilddrüse. Verhandlungen der deutschen Gesellschaft für Chirurgie, 1896, 25: 101-105.</ref><ref>{{WhoNamedIt|synd|3242}}</ref>
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==References==
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{{reflist|2}}
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{{Endocrine pathology}}
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[[de:Riedel-Struma]]
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[[it:Tiroidite di Riedel]]
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[[pl:Zapalenie gruczołu tarczowego Riedla]]

Revision as of 00:55, 15 January 2009

Riedel's thyroiditis
ICD-10 E06.5
ICD-9 245.3
DiseasesDB 11590
eMedicine med/2036 

Riedel's thyroiditis, also called Riedel's struma is a chronic form of thyroiditis.

Pathophysiology

Riedel's thyroiditis is characterized by a replacement of the normal thyroid parenchyma by a dense fibrosis that invades adjacent structures of the neck and extends beyond the thyroid capsule.[1] This makes the thyroid gland stone-hard and fixed to adjacent structures.

A shared mechanism with retroperitoneal fibrosis and sclerosing cholangitis has been suggested.[2]

Prevalence

Riedel's thyroiditis is classified as rare. Most patients remain euthyroid, but approximately 30% of patients become hypothyroid and very few patients are hyperthyroid. It is most seen in women.[3]

Treatment

Tamoxifen has been proposed as part of a treatment plan.[4]

Eponym

It is named for Bernhard Riedel. He first recognized the disease In 1883 and published its description in 1896.[5][6]

References

  1. Cho MH, Kim CS, Park JS; et al. (2007). "Riedel's thyroiditis in a patient with recurrent subacute thyroiditis: a case report and review of the literature". Endocr. J. 54 (4): 559–62. PMID 17603227. Unknown parameter |month= ignored (help)
  2. De Boer WA (1993). "Riedel's thyroiditis, retroperitoneal fibrosis, and sclerosing cholangitis: diseases with one pathogenesis?". Gut. 34 (5): 714. PMC 1374200. PMID 8504980. Unknown parameter |month= ignored (help)
  3. eMedicine
  4. Dabelic N, Jukic T, Labar Z, Novosel SA, Matesa N, Kusic Z (2003). "Riedel's thyroiditis treated with tamoxifen" (PDF). Croat. Med. J. 44 (2): 239–41. PMID 12698518. Unknown parameter |month= ignored (help)
  5. B. M. C. L. Riedel. Die chronische, zur Bildung eisenharter Tumoren führende Entzündung der Schilddrüse. Verhandlungen der deutschen Gesellschaft für Chirurgie, 1896, 25: 101-105.
  6. synd/3242 at Who Named It


de:Riedel-Struma it:Tiroidite di Riedel


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