Rhabdomyosarcoma classification: Difference between revisions
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**Early [[metastasis]] is common | **Early [[metastasis]] is common | ||
*Embryonal rhabdomyosarcoma | *Embryonal rhabdomyosarcoma | ||
**Usually affects children | **Usually affects children <10 years of age | ||
**Typically locally invasive | **Typically locally invasive | ||
*Botryoid rhabdomyosarcoma | *Botryoid rhabdomyosarcoma | ||
Revision as of 19:00, 11 September 2015
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Rhabdomyosarcoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Rhabdomyosarcoma classification On the Web |
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American Roentgen Ray Society Images of Rhabdomyosarcoma classification |
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Risk calculators and risk factors for Rhabdomyosarcoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Rhabdomyosarcoma may be classified according to the "International classification of rhabdomyosarcoma" into five subtypes: Alveolar rhabdomyosarcoma, embryonal rhabdomyosarcoma, botryoid rhabdomyosarcoma, spindle cell rhabdomyosarcoma, and anaplastic rhabdomyosarcoma.
Classification
Multiple classification systems have been proposed for subclassifying rhabdomyosarcomas. The most recent classification system, the "International classification of rhabdomyosarcoma", was created by the Intergroup Rhabdomyosarcoma Study.[1] This system attempts to combine elements of the previous systems and correlate these with prognosis based on tumor type. Rhabdomyosarcomas are classified into five subtypes:
- Alveolar rhabdomyosarcoma
- Usually affects young adults
- Early metastasis is common
- Embryonal rhabdomyosarcoma
- Usually affects children <10 years of age
- Typically locally invasive
- Botryoid rhabdomyosarcoma
- Spindle cell rhabdomyosarcoma
- Anaplastic rhabdomyosarcoma
Several additional subtypes of rhabdomyosarcoma exist that do not fit into the International Classification scheme:
- Pleomorphic rhabdomyosarcoma: Usually occurs in adults rather than children
- Sclerosing rhabdomyosarcoma: It is a rare rhabdomyosarcoma subtype
References
- ↑ Newton WA, Gehan EA, Webber BL; et al. (September 1995). "Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification—an Intergroup Rhabdomyosarcoma Study". Cancer. 76 (6): 1073–85. doi:10.1002/1097-0142(19950915)76:6<1073::AID-CNCR2820760624>3.0.CO;2-L. PMID 8625211.