Rhabdomyosarcoma classification: Difference between revisions
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Several additional subtypes of rhabdomyosarcoma exist that do not fit into the International Classification scheme: | Several additional subtypes of rhabdomyosarcoma exist that do not fit into the International Classification scheme: | ||
*Pleomorphic rhabdomyosarcoma: Usually occurs in adults rather than children | *Pleomorphic rhabdomyosarcoma: Usually occurs in adults rather than children | ||
*Sclerosing rhabdomyosarcoma: It is a rare rhabdomyosarcoma subtype recently characterized by Folpe, ''et al.''; it is not included in this system | *Sclerosing rhabdomyosarcoma: It is a rare rhabdomyosarcoma subtype recently characterized by Folpe, ''et al.''; it is not included in this system | ||
==References== | ==References== | ||
Revision as of 16:01, 8 September 2015
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Rhabdomyosarcoma Microchapters |
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Rhabdomyosarcoma classification On the Web |
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American Roentgen Ray Society Images of Rhabdomyosarcoma classification |
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Risk calculators and risk factors for Rhabdomyosarcoma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Rhabdomyosarcoma may be classified according to the "International classification of rhabdomyosarcoma" into six subtypes Alveolar rhabdomyosarcoma, embryonal rhabdomyosarcoma, botryoid rhabdomyosarcoma, spindle cell rhabdomyosarcoma, and undifferentiated rhabdomyosarcoma.
Classification
Multiple classification systems have been proposed for subclassifying rhabdomyosarcomas. The most recent classification system, the "International classification of rhabdomyosarcoma", was created by the Intergroup Rhabdomyosarcoma Study.[1] This system attempts to combine elements of the previous systems and correlate these with prognosis based on tumor type. Rhabdomyosarcomas classified into six subtypes:
- Alveolar rhabdomyosarcoma
- Usually affects young adults
- Early metastasis is common
- Usually arises in regions with skeletal muscle
- Embryonal rhabdomyosarcoma
- Usually affects children below 10 Years
- Typically locally invasive
- Usually arises in regions without skeletal muscle
- Botryoid rhabdomyosarcoma
- Spindle cell rhabdomyosarcoma
- Undifferentiated sarcoma
Several additional subtypes of rhabdomyosarcoma exist that do not fit into the International Classification scheme:
- Pleomorphic rhabdomyosarcoma: Usually occurs in adults rather than children
- Sclerosing rhabdomyosarcoma: It is a rare rhabdomyosarcoma subtype recently characterized by Folpe, et al.; it is not included in this system
References
- ↑ Newton WA, Gehan EA, Webber BL; et al. (September 1995). "Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification—an Intergroup Rhabdomyosarcoma Study". Cancer. 76 (6): 1073–85. doi:10.1002/1097-0142(19950915)76:6<1073::AID-CNCR2820760624>3.0.CO;2-L. PMID 8625211.