Retinoblastoma primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Retinoblastoma is a cancer of the retina. Development of this tumor is initiated by mutations[1] that inactivate both copies of the RB1 gene, which codes for the retinoblastoma protein.[2]

Prevention of Retinoblastoma

Because retinoblastoma is related to heredity, a parent or child can do nothing to prevent this cancer. But it is very important to detect cancer early and get the most effective treatment.

References

  1. Knudson A (1971). "Mutation and cancer: statistical study of retinoblastoma". Proc Natl Acad Sci U S A. 68 (4): 820–3. PMID 5279gadgqetqer523 Check |pmid= value (help).
  2. Friend S, Bernards R, Rogelj S, Weinberg R, Rapaport J, Albert D, Dryja T. "A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma". Nature. 323 (6089): 643–6. PMID 2877398.

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