Retinoblastoma primary prevention: Difference between revisions
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==Prevention of Retinoblastoma== | ==Prevention of Retinoblastoma== | ||
There are no known measures for preventing retinoblastoma. | There are no known measures for preventing retinoblastoma. Preimplantation genetic diagnosis has been performed, for families with a known germline [[mutation]]. In this procedure, embryos are fertilized using standard [[IVF]] techniques and are then biopsied at the eight cell stage. Only those embryos found to be free of the familial mutation in the retinoblastoma [[gene]] are implanted, resulting in a live birth of a healthy child.<ref name="pmid14700639">{{cite journal| author=Xu K, Rosenwaks Z, Beaverson K, Cholst I, Veeck L, Abramson DH| title=Preimplantation genetic diagnosis for retinoblastoma: the first reported liveborn. | journal=Am J Ophthalmol | year= 2004 | volume= 137 | issue= 1 | pages= 18-23 | pmid=14700639 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14700639 }} </ref> | ||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
There are no primary preventive measures available for retinoblastoma.
Prevention of Retinoblastoma
There are no known measures for preventing retinoblastoma. Preimplantation genetic diagnosis has been performed, for families with a known germline mutation. In this procedure, embryos are fertilized using standard IVF techniques and are then biopsied at the eight cell stage. Only those embryos found to be free of the familial mutation in the retinoblastoma gene are implanted, resulting in a live birth of a healthy child.[1]
References
- ↑ Xu K, Rosenwaks Z, Beaverson K, Cholst I, Veeck L, Abramson DH (2004). "Preimplantation genetic diagnosis for retinoblastoma: the first reported liveborn". Am J Ophthalmol. 137 (1): 18–23. PMID 14700639.