Retinoblastoma other diagnostic studies: Difference between revisions

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(Created page with "{{CMG}} {{Retinoblastoma}} ==Overview== '''Retinoblastoma''' is a cancer of the retina. Development of this tumor is initiated by mutations<ref>{{cite journal |au...")
 
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{{Retinoblastoma}}
==Overview==
==Biopsy/FNAC==
'''Retinoblastoma''' is a [[cancer]] of the [[retina]]. Development of this tumor is initiated by [[mutation]]s<ref>{{cite journal |author=Knudson A |title=Mutation and cancer: statistical study of retinoblastoma |journal=Proc Natl Acad Sci U S A |volume=68 |issue=4 |pages=820-3 |year=1971 |pmid=5279gadgqetqer523}}</ref> that inactivate both copies of the ''[[RB1]]'' gene, which codes for the [[retinoblastoma protein]].<ref>{{cite journal |author=Friend S, Bernards R, Rogelj S, Weinberg R, Rapaport J, Albert D, Dryja T |title=A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma |journal=Nature |volume=323 |issue=6089 |pages=643-6 |year= |pmid=2877398}}</ref>
Typical clinical and radiological findings make tissue biopsy confirmation unnecessary. It may also lead to extraocular seeding of tumor cells.


However, FNAC is indicated in special cases to confirm the diagnosis when the diagnosis is ambiguous and when there is already an obvious extraocular extension of the tunor.
==References==
==References==
<references/>
<references/>

Revision as of 17:58, 29 May 2012

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Biopsy/FNAC

Typical clinical and radiological findings make tissue biopsy confirmation unnecessary. It may also lead to extraocular seeding of tumor cells.


However, FNAC is indicated in special cases to confirm the diagnosis when the diagnosis is ambiguous and when there is already an obvious extraocular extension of the tunor.

References


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