Retinoblastoma differential diagnosis: Difference between revisions

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Revision as of 20:01, 11 October 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1],Associate Editor(s)-in-Chief: Jyostna Chouturi, M.B.B.S [2]

Overview

Retinoblastoma must be differentiated from other diseases that cause leukocoria, such as [differential dx1], [differential dx2], and [differential dx3].

Differential diagnosis

The common causes of leukocoria in children include:

Cataract
Persistent fetal vasculature
Coats disease

Less common causes of leukocoria include:

Coloboma (fissure or cleft) of choroid or optic disc
Toxocariasis
Astrocytic hamartoma
Retinopathy of prematurity (stage 4, 5)
Vitreous hemorrhage
Uveitis (pars planitis)
Retinal dysplasia

References

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@@ Line 4: / Line 4: @@
 ==Overview==
-Retinoblastoma must be differentiated from other diseases that cause leucokoria, strabismus, vision problems, eye pain such as cataract, and retinopathy of prematurity.
+Retinoblastoma must be differentiated from other diseases that cause leukocoria, such as [differential dx1], [differential dx2], and [differential dx3].
 ==Differential diagnosis==
-:1. Persistent hyperplastic primary vitreous (PHPV): congenital developmental anomaly of the eye resulting from failure of the embryological, primary vitreous and hyaloid vasculature to regress, whereby the eye is shorter, develops a cataract, and may present with whitening of the pupil.
+The common causes of leukocoria in children include:
-:2. [[Coats disease]]: a typically unilateral disease characterised by abnormal development of blood vessels behind the retina, leading to blood vessel abnormalities in the retina and retinal detachment to mimic retinoblastoma.
+*Cataract
-:3. [[Toxocara canis]]: an infectious disease of the eye associated with exposure to infected puppies, which causes a retinal lesion leading to retinal detachment.
+*Persistent fetal vasculature
-:4. [[Retinopathy of prematurity]] (ROP): associated with low birth weight infants who receive supplemental oxygen in the period immediately after birth, it involves damage to the retinal tissue and may lead to retinal detachment.
+*Coats disease
+Less common causes of leukocoria include:
-If the eye examination is abnormal, further testing may include imaging studies, such as [[computerized tomography]] (CT), [[magnetic resonance imaging]] (MRI), and [[ultrasound]].
+*Coloboma (fissure or cleft) of choroid or optic disc
+*Toxocariasis
+*Astrocytic hamartoma
+*Retinopathy of prematurity (stage 4, 5)
+*Vitreous hemorrhage
+*Uveitis (pars planitis)
+*Retinal dysplasia
 ==References==
 {{reflist|2}}

Retinoblastoma differential diagnosis: Difference between revisions

Revision as of 20:01, 11 October 2015

Overview

Differential diagnosis

References

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