Progeria epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Epidemiology and Demographics

Incidence

  • The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately one in four to eight million births worldwide.[1]
  • The incidence of Hutchinson-Gilford progeria syndrome (HGPS) in Netherlands is 1:4,000,000.[2]

Prevalence

  • The prevalence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately 1 in 20 million individuals worldwide.

Case-fatality rate/Mortality rate

  • In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
  • The case-fatality rate/mortality rate of [disease name] is approximately [number range].

Age

  • Patients of all age groups may develop [disease name].
  • The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
  • [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
  • [Chronic disease name] is usually first diagnosed among [age group].
  • [Acute disease name] commonly affects [age group].

Race

  • [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].

Gender

  • Hutchinson-Gilford progeria syndrome (HGPS) affects men and women equally but males are little more commonly affected by Hutchinson-Gilford progeria syndrome (HGPS) than females. The male to female ratio is approximately 1.2:1.[3]

Region

  • The majority of [disease name] cases are reported in [geographical region].
  • [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].

Developed Countries

Developing Countries

References

  1. Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
  2. Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
  3. Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.

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