Progeria history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]

Overview

The majority of patients with Hutchinson-Gilford progeria syndrome (HGPS) are growth issues, cardiac issues, ophthalmologic problems, hearing problems, failure to thrive, poor weight gain and prominent scalp veins.

History and Symptoms

  • The majority of patients with Hutchinson-Gilford progeria syndrome (HGPS) are asymptomatic in the first few months of life.
  • In patients with Hutchinson-Gilford progeria syndrome (HGPS) symptoms starts to appear in the first few years of life.

History

Patients with Hutchinson-Gilford progeria syndrome (HGPS) may have a positive history of:

Common Symptoms

Common symptoms of Hutchinson-Gilford progeria syndrome (HGPS) include:

Less Common Symptoms

Less common symptoms of Hutchinson-Gilford progeria syndrome (HGPS) include

  • Hyper/hypopigmentation
  • Dystrophic fingernails
  • Dystrophic toenails
  • Fingertip tufting

References


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