Pityriasis lichenoides et varioliformis acuta: Difference between revisions

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{{Infobox_Disease
{{Infobox_Disease
  | Name          = Pityriasis lichenoides et varioliformis acuta
  | Name          = Pityriasis lichenoides et varioliformis acuta
  | Image          = PLEVA.jpg
  | Image          = PLEVA.jpg  
| Caption        =
| DiseasesDB    =
| ICD10          = {{ICD10|L|41|0|l|40}}
| ICD9          = {{ICD9|696.2}}
| ICDO          =
| OMIM          =
| MedlinePlus    =
| eMedicineSubj  = derm
| eMedicineTopic = 334
| MeshID        =
}}
}}
__NOTOC__
__NOTOC__
{{SI}}
{{SI}}
{{CMG}}; {{AE}} {{KS}}
{{CMG}}; {{AE}} {{KS}}
{{SK}}


==Overview==
==Overview==
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==Historical Perspective==
==Historical Perspective==
*[Disease name] was first discovered by [scientist name], a [nationality + occupation], in [year] during/following [event].
 
*In [year], [gene] mutations were first identified in the pathogenesis of [disease name].
*In [year], the first [discovery] was developed by [scientist] to treat/diagnose [disease name].
   
   
==Classification==
==Classification==
*[Disease name] may be classified according to [classification method] into [number] subtypes/groups:
 
:*[group1]
:*[group2]
:*[group3]
*Other variants of [disease name] include [disease subtype 1], [disease subtype 2], and [disease subtype 3].
   
   
==Pathophysiology==
==Pathophysiology==
*The pathogenesis of [disease name] is characterized by [feature1], [feature2], and [feature3].
*The [gene name] gene/Mutation in [gene name] has been associated with the development of [disease name], involving the [molecular pathway] pathway.
*On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
*On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].


==Causes==
==Causes==
There is no known cause of this disease; however, many links from [[viruses]], [[vaccines]], and other illnesses have been made. The easiest way to understand this disease is to think of it like this:  Everyone has [[T cells]] that fight disease; in a person with PLEVA, the T cells get mixed up and decide to form in the skin, causing the lesions. It is unknown why this happens.


The trigger which causes the dysfunctional immune system response, PLEVA, is unknown; bacterial, viral, and environmental causes are suspected, but not conclusively demonstrated.
==Differentiating Pityriasis Lichenoides et Varoliformis Acuta from other Diseases==
*It is commonly misdiagnosed as chickenpox or [[rosacea]].


==Differentiating [disease name] from other Diseases==
*[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as:
:*[Differential dx1]
:*[Differential dx2]
:*[Differential dx3]
==Epidemiology and Demographics==
==Epidemiology and Demographics==
* The prevalence of [disease name] is approximately [number or range] per 100,000 individuals worldwide.
 
* In [year], the incidence of [disease name] was estimated to be [number or range] cases per 100,000 individuals in [location].
===Age===
===Age===
*Patients of all age groups may develop [disease name].
 
*[Disease name] is more commonly observed among patients aged [age range] years old.
*[Disease name] is more commonly observed among [elderly patients/young patients/children].
===Gender===
===Gender===
*[Disease name] affects men and women equally.
 
*[Gender 1] are more commonly affected with [disease name] than [gender 2].
* The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.
===Race===
===Race===
*There is no racial predilection for [disease name].
 
*[Disease name] usually affects individuals of the [race 1] race.
*[Race 2] individuals are less likely to develop [disease name].
==Risk Factors==
==Risk Factors==
*Common risk factors in the development of [disease name] are [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].
 
== Natural History, Complications and Prognosis==
== Natural History, Complications and Prognosis==
*The majority of patients with [disease name] remain asymptomatic for [duration/years].
*Prognosis is usually good with treatment.
*Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
*If left untreated, [#%] of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
*Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
*Prognosis is generally [excellent/good/poor], and the [1/5/10­year mortality/survival rate] of patients with [disease name] is approximately [#%].


==Diagnosis==
==Diagnosis==
===Diagnostic criteria===
===Diagnostic criteria===
It is commonly misdiagnosed as chickenpox or [[rosacea]]. The most common way to [[Diagnosis|diagnose]] is by [[biopsy]]. This disease has not been known to be life threatening. 
The most common way to [[Diagnosis|diagnose]] is by [[biopsy]].  


===History and Symptoms===
===History and Symptoms===
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===Laboratory Findings===
===Laboratory Findings===


===EKG===
===Imaging Findings===


===CT===
===Other Diagnostic Studies===


===X Ray===
==Treatment==


===Other imaging findings===
===Medical therapy===
 
===Other diagnostic studies===
 
==Treatment==
It is not contagious and currently there is no cure for the disease, although the lesions can be treated with [[Ultraviolet#Health effects|ultraviolet therapy]] as well as topical [[Steroid|steroids]] and [[Antibiotic|antibiotics]].   
It is not contagious and currently there is no cure for the disease, although the lesions can be treated with [[Ultraviolet#Health effects|ultraviolet therapy]] as well as topical [[Steroid|steroids]] and [[Antibiotic|antibiotics]].   


Treatment often involves multiple therapies that address the immune system and bacterial, viral, or dermatological causes.  
Treatment often involves multiple therapies that address the immune system and bacterial, viral, or dermatological causes.  
===Medical therapy===


===Surgery===
===Surgery===
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* {{DermNet|scaly/pityriasis-lichenoides}}
* {{DermNet|scaly/pityriasis-lichenoides}}


==References==
{{Reflist|2}}


{{Diseases of the skin and subcutaneous tissue}}
{{Diseases of the skin and subcutaneous tissue}}
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[[Category:Dermatology]]
[[Category:Dermatology]]


[[de:Pityriasis lichenoides et Varioliformis acuta]]


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Latest revision as of 15:53, 6 July 2016

Pityriasis lichenoides et varioliformis acuta

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Synonyms and keywords:

Overview

Pityriasis Lichenoides et Varioliformis Acuta, or Mucha Habermann's Disease, short form PLEVA, is a disease of the immune system. It is the more severe version of Pityriasis lichenoides chronica. The disease is characterized by rashes and small lesions on the skin. The disease is most common in males and usually occurs in childhood, although it has been seen in every age group and every race. It is possible for the disease to go into remission for short periods of time or forever.

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Pityriasis Lichenoides et Varoliformis Acuta from other Diseases

  • It is commonly misdiagnosed as chickenpox or rosacea.

Epidemiology and Demographics

Age

Gender

Race

Risk Factors

Natural History, Complications and Prognosis

  • Prognosis is usually good with treatment.

Diagnosis

Diagnostic criteria

The most common way to diagnose is by biopsy.

History and Symptoms

Physical Examination

Skin

Trunk

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical therapy

It is not contagious and currently there is no cure for the disease, although the lesions can be treated with ultraviolet therapy as well as topical steroids and antibiotics.

Treatment often involves multiple therapies that address the immune system and bacterial, viral, or dermatological causes.

Surgery

Prevention

See also

External links

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 "Dermatology Atlas".

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