Pityriasis lichenoides et varioliformis acuta: Difference between revisions

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{{Infobox_Disease
{{Infobox_Disease
  | Name          = Pityriasis lichenoides et varioliformis acuta
  | Name          = Pityriasis lichenoides et varioliformis acuta
  | Image          = PLEVA.jpg
  | Image          = PLEVA.jpg  
| Caption        =
| DiseasesDB    =
| ICD10          = {{ICD10|L|41|0|l|40}}
| ICD9          = {{ICD9|696.2}}
| ICDO          =
| OMIM          =
| MedlinePlus    =
| eMedicineSubj  = derm
| eMedicineTopic = 334
| MeshID        =
}}
}}
__NOTOC__
__NOTOC__
{{SI}}
{{SI}}
{{CMG}}; {{AE}} {{KS}}
{{CMG}}; {{AE}} {{KS}}
{{SK}}
==Overview==
==Overview==
'''[[Pityriasis]] Lichenoides et Varioliformis Acuta''', or '''Mucha Habermann's Disease''', short form '''PLEVA''', is a [[disease]] of the [[Immune system#Disorders of the human immune system|immune system]]. It is the more severe version of [[Pityriasis lichenoides chronica]]. The disease is characterized by [[rash]]es and small [[lesion]]s on the [[Skin#Aging and disease|skin]]. The disease is most common in males and usually occurs in childhood, although it has been seen in every age group and every race.  It is possible for the disease to go into [[remission]] for short periods of time or forever. 


==Historical Perspective==


'''[[Pityriasis]] Lichenoides et Varioliformis Acuta''', or '''Mucha Habermann's Disease''', short form '''PLEVA''', is a [[disease]] of the [[Immune system#Disorders of the human immune system|immune system]]. It is the more severe version of [[Pityriasis lichenoides chronica]]. The disease is characterized by [[rash]]es and small [[lesion]]s on the [[Skin#Aging and disease|skin]]. The disease is most common in males and usually occurs in childhood, although it has been seen in every age group and every race.  It is possible for the disease to go into [[remission]] for short periods of time or forever.  
   
==Classification==


==Diagnosis==
It is commonly misdiagnosed as chickenpox or [[rosacea]]. The most common way to [[Diagnosis|diagnose]] is by [[biopsy]].  This disease has not been known to be life threatening. 
==Pathophysiology==


==Causes==
==Causes==
There is no known cause of this disease; however, many links from [[viruses]], [[vaccines]], and other illnesses have been made. The easiest way to understand this disease is to think of it like this:  Everyone has [[T cells]] that fight disease; in a person with PLEVA, the T cells get mixed up and decide to form in the skin, causing the lesions. It is unknown why this happens.


The trigger which causes the dysfunctional immune system response, PLEVA, is unknown; bacterial, viral, and environmental causes are suspected, but not conclusively demonstrated.
==Differentiating Pityriasis Lichenoides et Varoliformis Acuta from other Diseases==
*It is commonly misdiagnosed as chickenpox or [[rosacea]].
 
==Epidemiology and Demographics==
 
===Age===
 
===Gender===
 
===Race===
 
==Risk Factors==
 
== Natural History, Complications and Prognosis==
*Prognosis is usually good with treatment.


==Diagnosis==
==Diagnosis==
===Diagnostic criteria===
The most common way to [[Diagnosis|diagnose]] is by [[biopsy]].   
===History and Symptoms===
===Physical Examination===
===Physical Examination===
====Skin====
====Skin====
Line 142: Line 158:


</gallery>
</gallery>
===Laboratory Findings===
===Imaging Findings===
===Other Diagnostic Studies===


==Treatment==
==Treatment==
===Medical therapy===
It is not contagious and currently there is no cure for the disease, although the lesions can be treated with [[Ultraviolet#Health effects|ultraviolet therapy]] as well as topical [[Steroid|steroids]] and [[Antibiotic|antibiotics]].   
It is not contagious and currently there is no cure for the disease, although the lesions can be treated with [[Ultraviolet#Health effects|ultraviolet therapy]] as well as topical [[Steroid|steroids]] and [[Antibiotic|antibiotics]].   


Treatment often involves multiple therapies that address the immune system and bacterial, viral, or dermatological causes.  
Treatment often involves multiple therapies that address the immune system and bacterial, viral, or dermatological causes.  
===Surgery===
===Prevention===


==See also==
==See also==
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* {{DermNet|scaly/pityriasis-lichenoides}}
* {{DermNet|scaly/pityriasis-lichenoides}}


==References==
{{Reflist|2}}


{{Diseases of the skin and subcutaneous tissue}}
{{Diseases of the skin and subcutaneous tissue}}
{{SIB}}
{{SIB}}


[[Category:Immune system disorders]]
[[Category:Immunology]]
[[Category:Rheumatology]]
[[Category:Dermatology]]
[[Category:Dermatology]]


[[de:Pityriasis lichenoides et Varioliformis acuta]]


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Latest revision as of 15:53, 6 July 2016

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Synonyms and keywords:

Overview

Pityriasis Lichenoides et Varioliformis Acuta, or Mucha Habermann's Disease, short form PLEVA, is a disease of the immune system. It is the more severe version of Pityriasis lichenoides chronica. The disease is characterized by rashes and small lesions on the skin. The disease is most common in males and usually occurs in childhood, although it has been seen in every age group and every race. It is possible for the disease to go into remission for short periods of time or forever.

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Pityriasis Lichenoides et Varoliformis Acuta from other Diseases

  • It is commonly misdiagnosed as chickenpox or rosacea.

Epidemiology and Demographics

Age

Gender

Race

Risk Factors

Natural History, Complications and Prognosis

  • Prognosis is usually good with treatment.

Diagnosis

Diagnostic criteria

The most common way to diagnose is by biopsy.

History and Symptoms

Physical Examination

Skin

Trunk

Laboratory Findings

Imaging Findings

Other Diagnostic Studies

Treatment

Medical therapy

It is not contagious and currently there is no cure for the disease, although the lesions can be treated with ultraviolet therapy as well as topical steroids and antibiotics.

Treatment often involves multiple therapies that address the immune system and bacterial, viral, or dermatological causes.

Surgery

Prevention

See also

External links

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 "Dermatology Atlas".

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