Pheochromocytoma causes: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 3: Line 3:
{{CMG}} {{AE}} {{AAM}} {{MAD}}
{{CMG}} {{AE}} {{AAM}} {{MAD}}
==Overview==
==Overview==
Pheochromocytoma develops in called [[chromaffin cells]], found in [[adrenal medulla]] which secrete [[adrenaline]], [[noradrenaline]]. Familial pheochromocytoma may be caused by a mutation of either ''[[VHL]]'', ''[[RET proto-oncogene|RET]]'', ''[[NF1]]'', ''[[SDHB]]'' or ''[[SDHD]]'' genes.
Pheochromocytoma develops in called [[chromaffin cells]], found in [[adrenal medulla]] which secretes [[adrenaline]], [[noradrenaline]], and [[Dopamine|dopamine.]] The genetic base of pheochromocytoma depends on 2 clusters: cluster 1 tumors are [[Norepinephrine|noradrenergic]]. Cluster 2 tumors are [[adrenergic]]. Familial pheochromocytoma may be caused by a mutation of either ''[[SDHD]],'' ''[[VHL]]'', ''[[SDHB]],'' ''[[RET proto-oncogene|RET]]'', ''[[NF1]]'' genes.
==Causes==
==Causes==
* Pheochromocytoma develops in called [[chromaffin cells]], found in the [[adrenal medulla]].   
* Pheochromocytoma develops in called [[chromaffin cells]], found in the [[adrenal medulla]].   

Revision as of 18:20, 31 July 2017

Pheochromocytoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Pheochromocytoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Pheochromocytoma causes On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Pheochromocytoma causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Pheochromocytoma causes

CDC on Pheochromocytoma causes

Pheochromocytoma causes in the news

Blogs on Pheochromocytoma causes

Directions to Hospitals Treating Pheochromocytoma

Risk calculators and risk factors for Pheochromocytoma causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2] Mohammed Abdelwahed M.D[3]

Overview

Pheochromocytoma develops in called chromaffin cells, found in adrenal medulla which secretes adrenaline, noradrenaline, and dopamine. The genetic base of pheochromocytoma depends on 2 clusters: cluster 1 tumors are noradrenergic. Cluster 2 tumors are adrenergic. Familial pheochromocytoma may be caused by a mutation of either SDHD, VHL, SDHB, RET, NF1 genes.

Causes

Cluster 1 Cluster 2

References

  1. King KS, Pacak K (2014). "Familial pheochromocytomas and paragangliomas". Mol Cell Endocrinol. 386 (1–2): 92–100. doi:10.1016/j.mce.2013.07.032. PMC 3917973. PMID 23933153.