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==FDA Package Insert==
==FDA Package Insert==
'''[[Ampicillin description|Description]]'''
'''[[Penicillin G potassium description|Description]]'''
'''| [[Ampicillin clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Penicillin G potassium clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Ampicillin microbiology|Microbiology]]'''
'''| [[Penicillin G potassium microbiology|Microbiology]]'''
'''| [[Ampicillin indications and usage|Indications and Usage]]'''
'''| [[Penicillin G potassium indications and usage|Indications and Usage]]'''
'''| [[Ampicillin contraindications|Contraindications]]'''
'''| [[Penicillin G potassium contraindications|Contraindications]]'''
'''| [[Ampicillin warnings and precautions|Warnings and Precautions]]'''
'''| [[Penicillin G potassium warnings and precautions|Warnings and Precautions]]'''
'''| [[Ampicillin adverse reactions|Adverse Reactions]]'''
'''| [[Penicillin G potassium adverse reactions|Adverse Reactions]]'''
'''| [[Ampicillin overdosage|Overdosage]]'''
'''| [[Penicillin G potassium overdosage|Overdosage]]'''
'''| [[Ampicillin dosage and administration|Dosage and Administration]]'''
'''| [[Penicillin G potassium dosage and administration|Dosage and Administration]]'''
'''| [[Ampicillin how supplied|How Supplied]]'''
'''| [[Penicillin G potassium how supplied|How Supplied]]'''
'''| [[Ampicillin labels and packages|Labels and Packages]]'''
'''| [[Penicillin G potassium labels and packages|Labels and Packages]]'''


==Mechanism of Action==
==Mechanism of Action==

Revision as of 00:43, 28 January 2014

Penicillin G potassium
PENICILLIN G POTASSIUM® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]

Overview

Buffered Penicillin G Potassium for Injection, USP is sterile penicillin G potassium powder for reconstitution. It is an antibacterial agent intended for intravenous or intramuscularly use. Buffered Penicillin G Potassium for Injection, USP is indicated in the treatment of serious infections caused by susceptible strains of the designated microorganisms in several conditions. Appropriate culture and susceptibility tests should be done before treatment in order to isolate and identify organisms causing infection and to determine their susceptibility to penicillin G.[1]

Category

beta-lactam antibiotics

US Brand Names

PENICILLIN G POTASSIUM®

FDA Package Insert

Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Dosage and Administration | How Supplied | Labels and Packages

Mechanism of Action

Penicillin G is bactericidal against penicillin-susceptible microorganisms during the stage of active multiplication. It acts by inhibiting biosynthesis of cell-wall mucopeptide. It is not active against the penicillinase-producing bacteria, which include many strains of staphylococci. Penicillin G is highly active in vitro against staphylococci (except penicillinase-producing strains), streptococci (groups A, B, C, G, H, L and M), pneumococci and Nelsseriameningitidis. Other organisms susceptible in vitro to penicillin G are Nelsseriagonorrhoeae, Corynebacteriumdiphtheriae, Bacillus anthracis, clostridia, Actinomycesspecies, Spirillum minus, Streptobacillusmonillformis, Listeria monocytogenes, and leptospira; Treponemapallidumis extremely susceptible.[1]

References

  1. 1.0 1.1 "PENICILLIN G POTASSIUM INJECTION, POWDER, FOR SOLUTION [SANDOZ INC]". Text " accessdate" ignored (help)

Adapted from the FDA Package Insert.