Papillary thyroid cancer staging: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
(Created page with "__NOTOC__ {{Papillary thyroid cancer}} {{CMG}}; {{AE}} {{Ammu}} ==Overview== ==Staging== ===Stage=== Based on overall cancer staging into stages I to IV, papillary thyroid...")
 
m (Bot: Removing from Primary care)
 
(24 intermediate revisions by 2 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Papillary thyroid cancer}}
{{Papillary thyroid cancer}}
{{CMG}}; {{AE}} {{Ammu}}
{{CMG}}; {{AE}} {{Ammu}} {{Sahar}}
==Overview==
==Overview==
According to the American Joint Committee on Cancer (AJCC) there are 4 stages of papillary thyroid cancer based on the [[clinical features]] and findings on [[imaging]]. Each stage is assigned a letter and a number that designate the [[tumor]] size, number of involved [[lymph node]] regions, and [[metastasis]].
==Staging==
==Staging==
===Stage===
* According to the American Joint Committee on Cancer (AJCC) there are 4 stages of papillary thyroid cancer based on the [[clinical features]] and findings on [[imaging]].<ref name="urlThyroid Cancer Treatment (Adult) (PDQ®)–Health Professional Version - National Cancer Institute">{{cite web |url=https://www.cancer.gov/types/thyroid/hp/thyroid-treatment-pdq#_441_toc |title=Thyroid Cancer Treatment (Adult) (PDQ®)–Health Professional Version - National Cancer Institute |format= |work= |accessdate=}}</ref>
Based on overall [[cancer staging]] into stages I to IV, papillary thyroid cancer has a [[5-year survival rate]] of 100 percent for stages I and II, 93 percent for stage III and 51 percent for stage IV.<ref name=acc>[http://www.cancer.org/cancer/thyroidcancer/detailedguide/thyroid-cancer-survival-rates cancer.org > Thyroid Cancer] By the American Cancer Society. In turn citing: AJCC Cancer Staging Manual (7th ed).</ref>
* Each stage is assigned a letter and a number that designate the [[tumor]] size, number of involved [[lymph node]] regions, and [[metastasis]].
{| class="wikitable"
|+
 
! colspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" + |Primary tumor
|-
| align="center" style="background:#f0f0f0;" |'''Tumor size'''
| align="center" style="background:#f0f0f0;" |'''Sub-stage'''
| align="center" style="background:#f0f0f0;" |'''Finding'''
|'''Image'''
|-
| T0
|  ||
* No evidence of primary [[tumor]]
|
|-
| T1
|  ||
* [[Tumor]] ≤2 cm in greatest dimension limited to the [[thyroid]]
|
|-
| T1
| a||
* [[Tumor]] ≤1 cm, limited to the [[thyroid]]
| [[Image:Diagram showing stage T1a thyroid cancer CRUK 250.png|200px|thumb|none]]
|-
| T1
| b||
* [[Tumor]] >1 cm but ≤2 cm in greatest dimension, limited to the [[thyroid]]
| [[Image:Diagram showing stage T1b thyroid cancer CRUK 251.svg.png|200px|thumb|none]]
|-
| T2
|  ||
* [[Tumor]] >2 cm but ≤4 cm in greatest dimension, limited to the [[thyroid]]
|
|-
| T3
|  ||
* [[Tumor]] >4 cm limited to the [[thyroid]], or gross extrathyroidal extension invading only strap [[muscles]]
| [[Image:Diagram showing stage T3 thyroid cancer CRUK 265.png|200px|thumb|none]]
|-
|T3
|a
|
* [[Tumor]] >4 cm limited to the [[thyroid]]
|
|-
|T3
|b
|
* Gross extrathyroidal extension invading only strap [[muscles]] ([[sternohyoid]], [[sternothyroid]], [[thyrohyoid]], or [[Omohyoid muscle|omohyoid muscles]]) from a [[tumor]] of any size
|
|-
| T4
|  ||
* [[Tumor]] includes gross extrathyroidal extension beyond the strap [[muscles]]
|
|-
| T4
| a||
* [[Tumor]] with gross extrathyroidal extension invading subcutaneous [[Soft tissue|soft tissues]], [[larynx]], [[trachea]], [[esophagus]], or [[recurrent laryngeal nerve]] from a [[tumor]] of any size
|[[Image:Diagram showing stage T4a thyroid cancer CRUK 272.png|200px|thumb|none]]
|-
| T4
| b||
* [[Tumor]] with gross extrathyroidal extension invading [[prevertebral fascia]] or encasing the [[carotid artery]] or [[mediastinal]] vessels from a [[tumor]] of any size.
|[[Image:Diagram showing stage T4b thyroid cancer CRUK 273.png|200px|thumb|none]]
|-
| TX
|  ||
* Primary [[tumor]] cannot be assessed
|
|-
|+
 
! colspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" + |Regional lymph node involvement
|-
| align="center" style="background:#f0f0f0;" |'''Node involvement'''
| align="center" style="background:#f0f0f0;" |'''Sub-stage'''
| align="center" style="background:#f0f0f0;" |'''Finding'''
|'''Image'''
|-
| N0
| ||
* No [[lymph node]] involvement
|
|-
|N0
|a
|
* One or more cytologically or [[histologically]] confirmed benign [[lymph nodes]]
|
|-
|N0
|b
|
* No [[Radiological|radiologic]] or clinical evidence of locoregional [[lymph node]] [[metastasis]]
|
|-
| N1
|  ||
* [[Metastasis]] to regional nodes
|
|-
| N1
| a||
* [[Metastasis]] to level VI or VII ([[Pretracheal lymph nodes|pretracheal]], [[Paratracheal lymph nodes|paratracheal]], or [[Prelaryngeal lymph nodes|prelaryngeal]]/Delphian, or upper mediastinal) [[lymph nodes]]. This can be unilateral or bilateral [[disease]]
|[[Image:Diagram showing stage N1a thyroid cancer CRUK 242.png|200px|thumb|none]]
|-
| N1
| b||
* [[Metastasis]] to unilateral, bilateral, or contralateral [[Cervical lymph nodes|cervical]] neck [[lymph nodes]] (levels I, II, III, IV, or V) or [[retropharyngeal lymph nodes]]
|[[Image:Diagram showing stage N1b thyroid cancer CRUK 243.png|200px|thumb|none]]
|-
| NX
|  ||
* Regional [[lymph node]] cannot be assessed
|
|-
|+
 
! colspan="4" style="background:#4479BA; color: #FFFFFF;" align="center" + |Distant metastasis
|-
| align="center" style="background:#f0f0f0;" |'''Presence of metastasis'''
| align="center" style="background:#f0f0f0;" |'''Sub-stage'''
| align="center" style="background:#f0f0f0;" |'''Finding'''
|'''Image'''
|-
| M0
| ||
* No distant [[metastasis]]
|
|-
| M1
| IV||
* Distant [[metastasis]]
|[[Image:Stage M1 Thyroid cancer.png|200px|thumb|none]]
|-
|}
 
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
|+
 
|-
 
|-
 
|-
 
|-
 
|-
 
|-
 
|-
 
|-
 
|-
 
|-
 
|-
 
|}
<br />
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
|+'''''Anatomic Stage/Prognostic Groups'''''
! style="background: #4479BA; width: 120px;" | {{fontcolor|#FFF|Stage}}
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|T}}
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|N}}
! style="background: #4479BA; width: 550px;" | {{fontcolor|#FFF|M}}
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" colspan=4 align=center| '''Papillary thyroid carcinoma'''
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" colspan=4 | '''Younger than 55 years'''
|-
! style="background: #DCDCDC;" |I
! style="background: #F5F5F5;" |Any T
 
! style="background: #F5F5F5;" |Any N
 
! style="background: #F5F5F5;" |M0
|-
! style="background: #DCDCDC;" |II
! style="background: #F5F5F5;" |Any T
 
! style="background: #F5F5F5;" |Any N
 
! style="background: #F5F5F5;" |M1
 
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" colspan=4 | '''55 years and older'''
|-
! style="background: #DCDCDC;" |I
! style="background: #F5F5F5;" |T1
! style="background: #F5F5F5;" |Any N
! style="background: #F5F5F5;" |M0
|-
! rowspan="4" style="background: #DCDCDC;" |II
! style="background: #F5F5F5;" |T1
! style="background: #F5F5F5;" |N1
! style="background: #F5F5F5;" |M0
|-
! style="background: #F5F5F5;" |T2
! style="background: #F5F5F5;" |N1
! style="background: #F5F5F5;" |M0
 
|-
! style="background: #F5F5F5;" |T3a
! style="background: #F5F5F5;" |Any N
! style="background: #F5F5F5;" |M0
 
|-
! style="background: #F5F5F5;" |T3b
! style="background: #F5F5F5;" |Any N
! style="background: #F5F5F5;" |M0
 
|-
 
! style="background: #DCDCDC;" |III
! style="background: #F5F5F5;" |T4a
! style="background: #F5F5F5;" |Any N
! style="background: #F5F5F5;" |M0
 
|-
 
! style="background: #DCDCDC;" |IVA
! style="background: #F5F5F5;" |T4b
! style="background: #F5F5F5;" |Any N
! style="background: #F5F5F5;" |M0
 
|-
 
! rowspan="6" style="background: #DCDCDC;" |IVB
! style="background: #F5F5F5;" |Any T
! style="background: #F5F5F5;" |Any N
! style="background: #F5F5F5;" |M1
 
|-
! style="background: #F5F5F5;" |T1
! style="background: #F5F5F5;" |N1
! style="background: #F5F5F5;" |M0
 
|-
! style="background: #F5F5F5;" |T2
! style="background: #F5F5F5;" |N1
! style="background: #F5F5F5;" |M0
 
|-
! style="background: #F5F5F5;" |T3a
! style="background: #F5F5F5;" |N1
! style="background: #F5F5F5;" |M0
 
|-
! style="background: #F5F5F5;" |T3b
! style="background: #F5F5F5;" |Any N
! style="background: #F5F5F5;" |M0
 
|-
! style="background: #F5F5F5;" |T4
! style="background: #F5F5F5;" |Any N
! style="background: #F5F5F5;" |M0
 
|-
 
! style="background: #DCDCDC;" |IVC
! style="background: #F5F5F5;" |Any T
! style="background: #F5F5F5;" |Any N
! style="background: #F5F5F5;" |M1
|}
 
==Reference==
{{Reflist|2}}
 
[[Category:Endocrine system]]
[[Category:Endocrinology]]
[[Category:Otolaryngology]]
[[Category:Disease]]
[[Category:Genetic disorders]]
[[Category:Types of cancer]]
[[Category:Hereditary cancers]]
[[Category:Thyroid disease]]

Latest revision as of 23:34, 29 July 2020

Papillary thyroid cancer Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Papillary thyroid cancer from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Papillary thyroid cancer staging On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Papillary thyroid cancer staging

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Papillary thyroid cancer staging

CDC on Papillary thyroid cancer staging

Papillary thyroid cancer staging in the news

Blogs on Papillary thyroid cancer staging

Directions to Hospitals Treating Papillary thyroid cancer

Risk calculators and risk factors for Papillary thyroid cancer staging

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2] Sahar Memar Montazerin, M.D.[3]

Overview

According to the American Joint Committee on Cancer (AJCC) there are 4 stages of papillary thyroid cancer based on the clinical features and findings on imaging. Each stage is assigned a letter and a number that designate the tumor size, number of involved lymph node regions, and metastasis.

Staging

  • According to the American Joint Committee on Cancer (AJCC) there are 4 stages of papillary thyroid cancer based on the clinical features and findings on imaging.[1]
  • Each stage is assigned a letter and a number that designate the tumor size, number of involved lymph node regions, and metastasis.
Primary tumor
Tumor size Sub-stage Finding Image
T0
  • No evidence of primary tumor
T1
T1 a
T1 b
  • Tumor >1 cm but ≤2 cm in greatest dimension, limited to the thyroid
T2
  • Tumor >2 cm but ≤4 cm in greatest dimension, limited to the thyroid
T3
  • Tumor >4 cm limited to the thyroid, or gross extrathyroidal extension invading only strap muscles
T3 a
T3 b
T4
  • Tumor includes gross extrathyroidal extension beyond the strap muscles
T4 a
T4 b
TX
  • Primary tumor cannot be assessed
Regional lymph node involvement
Node involvement Sub-stage Finding Image
N0
N0 a
N0 b
N1
N1 a
N1 b
NX
Distant metastasis
Presence of metastasis Sub-stage Finding Image
M0
M1 IV


Anatomic Stage/Prognostic Groups
Stage T N M
Papillary thyroid carcinoma
Younger than 55 years
I Any T Any N M0
II Any T Any N M1
55 years and older
I T1 Any N M0
II T1 N1 M0
T2 N1 M0
T3a Any N M0
T3b Any N M0
III T4a Any N M0
IVA T4b Any N M0
IVB Any T Any N M1
T1 N1 M0
T2 N1 M0
T3a N1 M0
T3b Any N M0
T4 Any N M0
IVC Any T Any N M1

Reference

  1. ↑ "Thyroid Cancer Treatment (Adult) (PDQ®)–Health Professional Version - National Cancer Institute".
Retrieved from "https://www.wikidoc.org/index.php?title=Papillary_thyroid_cancer_staging&oldid=1641806"