POEMS syndrome other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
(18)F-FDG [[Positron emission tomography|PET]]/[[Computed tomography|CT]] is an adequate tool for evaluation, [[diagnosis]], and monitoring of the [[pathology]]. (18)F-FDG [[Positron emission tomography|PET]]/[[Computed tomography|CT]] may be helpful in the [[diagnosis]] of POEMS [[syndrome]]. Findings suggestive of POEMS [[syndrome]] include mixed [[bone]] [[Lesion|lesions]], [[lymphadenopathy]], [[hepatosplenomegaly]], and [[Serous membrane|serous cavity]] effusions. Fluorescein angiography may reveal unilateral pooling of fluid consistent with cystoid macular edema. | (18)F-FDG [[Positron emission tomography|PET]]/[[Computed tomography|CT]] is an adequate tool for evaluation, [[diagnosis]], and monitoring of the [[pathology]]. (18)F-FDG [[Positron emission tomography|PET]]/[[Computed tomography|CT]] may be helpful in the [[diagnosis]] of POEMS [[syndrome]]. Findings suggestive of POEMS [[syndrome]] include mixed [[bone]] [[Lesion|lesions]], [[lymphadenopathy]], [[hepatosplenomegaly]], and [[Serous membrane|serous cavity]] effusions. [[Fluorescein angiography]] may reveal unilateral pooling of [[fluid]] consistent with [[Macular edema|cystoid macular edema]]. [[Optical coherence tomography|Optical coherence tomography (OCT)]] may show loss of [[retinal]] [[nerve]] fiber layer thickness. | ||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
*[[Fluorescein angiography]] may reveal pooling of [[fluid]] consistent with [[Macular edema|cystoid macular edema]].<ref name="pmid17554492">{{cite journal |vauthors=Okada K, Yamamoto S, Tsuyama Y, Mizunoya S |title=Case of POEMS syndrome associated with bilateral macular detachment resolved by autologous peripheral blood stem cell transplantation |journal=Jpn. J. Ophthalmol. |volume=51 |issue=3 |pages=237–8 |date=2007 |pmid=17554492 |doi=10.1007/s10384-006-0428-8 |url=}}</ref><ref name="pmid19123170">{{cite journal |vauthors=Gutierrez-Ortiz C, Castro-Rebollo M, Pareja J, Beckford C, Teus M |title=Bilateral non-simultaneous optic neuropathy and unilateral macular edema in a patient with POEMS syndrome |journal=Eur J Ophthalmol |volume=19 |issue=1 |pages=166–9 |date=2009 |pmid=19123170 |doi= |url=}}</ref> | |||
*[[Optical coherence tomography|Optical coherence tomography (OCT)]] may show loss of [[retinal]] [[nerve]] fiber layer thickness.<ref name="pmid19123170">{{cite journal |vauthors=Gutierrez-Ortiz C, Castro-Rebollo M, Pareja J, Beckford C, Teus M |title=Bilateral non-simultaneous optic neuropathy and unilateral macular edema in a patient with POEMS syndrome |journal=Eur J Ophthalmol |volume=19 |issue=1 |pages=166–9 |date=2009 |pmid=19123170 |doi= |url=}}</ref> | |||
*(18)F-FDG [[Positron emission tomography|PET]]/[[Computed tomography|CT]] is an adequate tool for evaluation, [[diagnosis]], and monitoring of the [[pathology]].<ref name="pmid30713387">{{cite journal |vauthors=Infante JR, García L, Rayo JI, Serrano J, Moreno M, Cobo A, Jimenez P, Martínez A |title=Positron Emission Tomography-Computed Tomography in a Case of POEMS Syndrome |journal=Indian J Nucl Med |volume=34 |issue=1 |pages=66–68 |date=2019 |pmid=30713387 |doi=10.4103/ijnm.IJNM_120_18 |url=}}</ref> | *(18)F-FDG [[Positron emission tomography|PET]]/[[Computed tomography|CT]] is an adequate tool for evaluation, [[diagnosis]], and monitoring of the [[pathology]].<ref name="pmid30713387">{{cite journal |vauthors=Infante JR, García L, Rayo JI, Serrano J, Moreno M, Cobo A, Jimenez P, Martínez A |title=Positron Emission Tomography-Computed Tomography in a Case of POEMS Syndrome |journal=Indian J Nucl Med |volume=34 |issue=1 |pages=66–68 |date=2019 |pmid=30713387 |doi=10.4103/ijnm.IJNM_120_18 |url=}}</ref> | ||
*(18)F-FDG [[Positron emission tomography|PET]]/[[CT]] may be helpful in the [[diagnosis]] of POEMS [[syndrome]]. Findings suggestive of POEMS [[syndrome]] include: | *(18)F-FDG [[Positron emission tomography|PET]]/[[CT]] may be helpful in the [[diagnosis]] of POEMS [[syndrome]]. Findings suggestive of POEMS [[syndrome]] include: | ||
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**[[Splenomegaly]]<ref name="pmid26182964">{{cite journal |vauthors=Pan Q, Li J, Li F, Zhou D, Zhu Z |title=Characterizing POEMS Syndrome with 18F-FDG PET/CT |journal=J. Nucl. Med. |volume=56 |issue=9 |pages=1334–7 |date=September 2015 |pmid=26182964 |doi=10.2967/jnumed.115.160507 |url=}}</ref> | **[[Splenomegaly]]<ref name="pmid26182964">{{cite journal |vauthors=Pan Q, Li J, Li F, Zhou D, Zhu Z |title=Characterizing POEMS Syndrome with 18F-FDG PET/CT |journal=J. Nucl. Med. |volume=56 |issue=9 |pages=1334–7 |date=September 2015 |pmid=26182964 |doi=10.2967/jnumed.115.160507 |url=}}</ref> | ||
**[[Serous membrane|Serous cavity]] effusions<ref name="pmid26182964">{{cite journal |vauthors=Pan Q, Li J, Li F, Zhou D, Zhu Z |title=Characterizing POEMS Syndrome with 18F-FDG PET/CT |journal=J. Nucl. Med. |volume=56 |issue=9 |pages=1334–7 |date=September 2015 |pmid=26182964 |doi=10.2967/jnumed.115.160507 |url=}}</ref> | **[[Serous membrane|Serous cavity]] effusions<ref name="pmid26182964">{{cite journal |vauthors=Pan Q, Li J, Li F, Zhou D, Zhu Z |title=Characterizing POEMS Syndrome with 18F-FDG PET/CT |journal=J. Nucl. Med. |volume=56 |issue=9 |pages=1334–7 |date=September 2015 |pmid=26182964 |doi=10.2967/jnumed.115.160507 |url=}}</ref> | ||
==References== | ==References== | ||
Latest revision as of 22:18, 6 February 2019
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POEMS syndrome other imaging findings On the Web |
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American Roentgen Ray Society Images of POEMS syndrome other imaging findings |
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Risk calculators and risk factors for POEMS syndrome other imaging findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]
Overview
(18)F-FDG PET/CT is an adequate tool for evaluation, diagnosis, and monitoring of the pathology. (18)F-FDG PET/CT may be helpful in the diagnosis of POEMS syndrome. Findings suggestive of POEMS syndrome include mixed bone lesions, lymphadenopathy, hepatosplenomegaly, and serous cavity effusions. Fluorescein angiography may reveal unilateral pooling of fluid consistent with cystoid macular edema. Optical coherence tomography (OCT) may show loss of retinal nerve fiber layer thickness.
Other Imaging Findings
- Fluorescein angiography may reveal pooling of fluid consistent with cystoid macular edema.[1][2]
- Optical coherence tomography (OCT) may show loss of retinal nerve fiber layer thickness.[2]
- (18)F-FDG PET/CT is an adequate tool for evaluation, diagnosis, and monitoring of the pathology.[3]
- (18)F-FDG PET/CT may be helpful in the diagnosis of POEMS syndrome. Findings suggestive of POEMS syndrome include:
- Mixed bone lesions (lytic and sclerotic)[4][3]
- Lymphadenopathy[4]
- Hepatomegaly[4]
- Splenomegaly[4]
- Serous cavity effusions[4]
References
- ↑ Okada K, Yamamoto S, Tsuyama Y, Mizunoya S (2007). "Case of POEMS syndrome associated with bilateral macular detachment resolved by autologous peripheral blood stem cell transplantation". Jpn. J. Ophthalmol. 51 (3): 237–8. doi:10.1007/s10384-006-0428-8. PMID 17554492.
- ↑ 2.0 2.1 Gutierrez-Ortiz C, Castro-Rebollo M, Pareja J, Beckford C, Teus M (2009). "Bilateral non-simultaneous optic neuropathy and unilateral macular edema in a patient with POEMS syndrome". Eur J Ophthalmol. 19 (1): 166–9. PMID 19123170.
- ↑ 3.0 3.1 Infante JR, García L, Rayo JI, Serrano J, Moreno M, Cobo A, Jimenez P, Martínez A (2019). "Positron Emission Tomography-Computed Tomography in a Case of POEMS Syndrome". Indian J Nucl Med. 34 (1): 66–68. doi:10.4103/ijnm.IJNM_120_18. PMID 30713387.
- ↑ 4.0 4.1 4.2 4.3 4.4 Pan Q, Li J, Li F, Zhou D, Zhu Z (September 2015). "Characterizing POEMS Syndrome with 18F-FDG PET/CT". J. Nucl. Med. 56 (9): 1334–7. doi:10.2967/jnumed.115.160507. PMID 26182964.