POEMS syndrome epidemiology and demographics

Jump to navigation Jump to search

POEMS syndrome Microchapters

Home

Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Differentiating POEMS syndrome from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

POEMS syndrome epidemiology and demographics On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of POEMS syndrome epidemiology and demographics

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on POEMS syndrome epidemiology and demographics

CDC on POEMS syndrome epidemiology and demographics

POEMS syndrome epidemiology and demographics in the news

Blogs on POEMS syndrome epidemiology and demographics

Directions to Hospitals Treating POEMS syndrome

Risk calculators and risk factors for POEMS syndrome epidemiology and demographics

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]

Overview

The precise incidence of POEMS syndrome is difficult to determine and we have no well established data to quote. The median age at presentation has been 51 years with the majority of the patients comprising of males. A median survival of 165 months has also been recorded. The precise incidence of POEMS syndrome is difficult to determine due to the complexity of the syndrome presentation and we have no well established data regarding the incidence. Prevalence of POEMS syndrome in Japan is reported to be about 0.3 per 100,000 individuals. There is no racial predilection to POEMS syndrome. There is no well established data regarding the gender predilection of POEMS syndrome. Data from Japan shows a male predilection of 2.5:1. The majority of POEMS syndrome cases have been reported in Japan and China.

Epidemiology and Demographics

Incidence

The precise incidence of POEMS syndrome is difficult to determine due to the complexity of the syndrome presentation and we have no well established data regarding the incidence.

Prevalence

Prevalence of POEMS syndrome in Japan is reported to be about 0.3 per 100,000 individuals.[1]

Age

The median age at presentation is 51 years.[2]

Race

There is no racial predilection to POEMS syndrome.[3][4][5]

Gender

  • There is no well established data regarding the gender predilection of POEMS syndrome.
  • Data from Japan shows a male predilection of 2.5:1.[6]

Region

The majority of POEMS syndrome cases have been reported in Japan and China.[3][4][5]

References

  1. https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=2905
  2. Dispenzieri A, Kyle RA, Lacy MQ, Rajkumar SV, Therneau TM, Larson DR, Greipp PR, Witzig TE, Basu R, Suarez GA, Fonseca R, Lust JA, Gertz MA (April 2003). "POEMS syndrome: definitions and long-term outcome". Blood. 101 (7): 2496–506. doi:10.1182/blood-2002-07-2299. PMID 12456500.
  3. 3.0 3.1 Yuan M, Chen W, Zhou H, Xiao Z, Wang W, Wang W, Yin X, Xu L (2016). "Kennedy Disease Misdiagnosed as Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy, and Skin Changes (POEMS) Syndrome: A Case Report". Med Princ Pract. 25 (3): 286–9. doi:10.1159/000442822. PMC 5588369. PMID 26618536.
  4. 4.0 4.1 Tang LM, Chen ST, Cheng SY, Lyu RK (1995). "POEMS syndrome in Chinese". Eur. Neurol. 35 (6): 349–53. doi:10.1159/000117159. PMID 8591803.
  5. 5.0 5.1 Romas E, Storey E, Ayers M, Byrne E (July 1992). "Polyneuropathy, organomegaly, endocrinopathy, M-protein and skin change (POEMS) syndrome with IgG kappa paraproteinemia". Pathology. 24 (3): 217–20. PMID 1437299.
  6. https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=2905

Template:WikiDoc Sources