Optic nerve glioma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

History and Symptoms

History

Patients with optic pathway gliomas most frequently present in the first decade with a median age of 6.5 years, with slowly progressive visual loss, followed later by proptosis (although this sequence may occasionally be reversed). Acute visual loss due to hemorrhage into the tumor is uncommon.

Common Symptoms

The symptoms are due to the tumor growing and pressing on the optic nerve and nearby structures. Symptoms may include:

  • Involuntary eyeball movement
  • Outward bulging of one or both eyes
  • Squinting
  • Vision loss in one or both eyes that starts with the loss of peripheral vision and eventually leads to blindness
  • The child may show symptoms of diencephalic syndrome, which includes:
    • Daytime sleeping
    • Decreased memory and brain function
    • Delayed growth
    • Loss of appetite and body fat

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