Optic nerve glioma epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Epidemiology and Demographics
Optic nerve gliomas typically present in children, and often in the setting of NF1 (10-63%). In this setting, the tumors are often low grade and indolent. In adults, optic nerve gliomas do occur but are very rare and usually aggressive tumors. In such cases no association with NF1 has been found. 5 % of all childhood brain tumors account for optic nerve gliomas. About 1% of all intracranial tumors are comprised of optic-nerve gliomas. It is most common in children who have the genetic condition neurofibromatosis 1 (NF1). Most optic gliomas are slow-growing and noncancerous and occur in children, almost always before age 20. Optic nerve glioma is a rare kind of cancer, usually slow-growing and found in children. 90 percent of optic nerve gliomas are diagnosed before the age of 20. 75 percent of optic nerve gliomas are diagnosed before the age of 10, 50 percent before the age of 5 and 25 percent before the age of 18 months. As many as 70% of optic nerve tumors are associated with NF1. The mean age of presentation of optic nerve gliomas is 8.8 years.
Prevalence
Prevalence of optic nerve glioma is approximately 1 per 100,000 patients presenting with eye complaints.
Incidence
Gender
Boys and girls are equally affected.
Age
75% of people with optic pathway gliomas are younger than 10 years of age. The mean age of presentation of optic nerve glioma is 8.8 years.
Race
There are no racial or ethnic groups that are at more risk than others of optic nerve gliomas.