Onchocerciasis: Difference between revisions

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{{CMG}} {{AE}} {{KD}}
{{CMG}} {{AE}} {{KD}}


{{SK}} Onchocercosis; river blindness; Robles disease
{{SK}} Onchocercosis; river blindness; Robles disease; onchocerca volvulus infection
==[[Onchocerciasis overview|Overview]]==
==[[Onchocerciasis overview|Overview]]==
==[[Onchocerciasis historical perspective|Historical Perspective]]==
==[[Onchocerciasis historical perspective|Historical Perspective]]==
==[[Onchocerciasis classification|Classification]]==


==[[Onchocerciasis pathophysiology|Pathophysiology]]==
==[[Onchocerciasis pathophysiology|Pathophysiology]]==
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==[[Onchocerciasis epidemiology and demographics|Epidemiology and Demographics]]==
==[[Onchocerciasis epidemiology and demographics|Epidemiology and Demographics]]==
==[[Onchocerciasis risk factors|Risk Factors]]==


==[[Onchocerciasis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
==[[Onchocerciasis natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
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==Treatment==
==Treatment==
[[Onchocerciasis medical therapy|Medical Therapy]] | [[Onchocerciasis primary prevention|Primary Prevention]] | [[Onchocerciasis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Onchocerciasis future or investigational therapies|Future or Investigational Therapies]]
[[Onchocerciasis medical therapy|Medical Therapy]] | [[Onchocerciasis primary prevention|Primary Prevention]] | [[Onchocerciasis cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Onchocerciasis future or investigational therapies|Future or Investigational Therapies]]
===Antimicrobial therapy===
:* '''Cutaneous filariasis - Onchocercia volvulus, Loa loa'''<ref name="pmid20739055">{{cite journal| author=Taylor MJ, Hoerauf A, Bockarie M| title=Lymphatic filariasis and onchocerciasis. | journal=Lancet | year= 2010 | volume= 376 | issue= 9747 | pages= 1175-85 | pmid=20739055 | doi=10.1016/S0140-6736(10)60586-7 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20739055  }} </ref><ref name="pmid22632644">{{cite journal| author=Knopp S, Steinmann P, Hatz C, Keiser J, Utzinger J| title=Nematode infections: filariases. | journal=Infect Dis Clin North Am | year= 2012 | volume= 26 | issue= 2 | pages= 359-81 | pmid=22632644 | doi=10.1016/j.idc.2012.02.005 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22632644  }} </ref>
::* Preferred regimen (1): [[Doxycycline]] 150 μg/kg single dose
::* Preferred regimen (2): ([[Doxycycline]] 100 mg PO qd for 6 weeks {{or}} 200 mg PO qd for 4 weeks) {{then}} [[Ivermectin]] after 4-6 months 150 μg/kg single dose
::* Preferred regimen (3): [[Doxycycline]] 200 mg PO qd for 6 weeks {{then}} [[Ivermectin]] after 4-6 months 150 μg/kg single dose
==Case Studies==
==Case Studies==
[[Onchocerciasis case study one|Case #1]]
[[Onchocerciasis case study one|Case #1]]
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[[Category:Neglected diseases]]
[[Category:Neglected diseases]]
[[Category:Disease]]
[[Category:Disease]]
[[Category:Infectious disease]]
 


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[[de:Onchozerkose]]
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{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WS}}
{{WS}}
==References==
{{reflist|2}}

Latest revision as of 18:31, 18 September 2017

Onchocerca volvulus
O. volvulus, the causative agent of river blindness.
O. volvulus, the causative agent of river blindness.
Scientific classification
Kingdom: Animalia
Phylum: Nematoda
Class: Secernentea
Order: Spirurida
Family: Filariidae
Genus: Onchocerca
Species: O. volvulus
Binomial name
Onchocerca volvulus
Bickel 1982

Onchocerciasis Microchapters

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History and Symptoms

Physical Examination

Laboratory Findings

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Treatment

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Case #1

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For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalsang Dolma, M.B.B.S.[2]

Synonyms and keywords: Onchocercosis; river blindness; Robles disease; onchocerca volvulus infection

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Onchocerciasis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms | Physical Examination | Laboratory Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Primary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Antimicrobial therapy

  • Cutaneous filariasis - Onchocercia volvulus, Loa loa[1][2]
  • Preferred regimen (1): Doxycycline 150 μg/kg single dose
  • Preferred regimen (2): (Doxycycline 100 mg PO qd for 6 weeks OR 200 mg PO qd for 4 weeks) THEN Ivermectin after 4-6 months 150 μg/kg single dose
  • Preferred regimen (3): Doxycycline 200 mg PO qd for 6 weeks THEN Ivermectin after 4-6 months 150 μg/kg single dose


Case Studies

Case #1

External Links


Template:Helminthiases


de:Onchozerkose it:Oncocercosi fi:Jokisokeus


Template:WS

References

  1. Taylor MJ, Hoerauf A, Bockarie M (2010). "Lymphatic filariasis and onchocerciasis". Lancet. 376 (9747): 1175–85. doi:10.1016/S0140-6736(10)60586-7. PMID 20739055.
  2. Knopp S, Steinmann P, Hatz C, Keiser J, Utzinger J (2012). "Nematode infections: filariases". Infect Dis Clin North Am. 26 (2): 359–81. doi:10.1016/j.idc.2012.02.005. PMID 22632644.