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Computed tomography is the method of choice for the diagnosis of non-small cell lung cancer.<ref name="pmid8190965">{{cite journal |vauthors=Rosado-de-Christenson ML, Templeton PA, Moran CA |title=Bronchogenic carcinoma: radiologic-pathologic correlation |journal=Radiographics |volume=14 |issue=2 |pages=429–46; quiz 447–8 |year=1994 |pmid=8190965 |doi=10.1148/radiographics.14.2.8190965 |url=}}</ref><ref name="pmid19234288">{{cite journal |vauthors=Parker MS, Chasen MH, Paul N |title=Radiologic signs in thoracic imaging: case-based review and self-assessment module |journal=AJR Am J Roentgenol |volume=192 |issue=3 Suppl |pages=S34–48 |year=2009 |pmid=19234288 |doi=10.2214/AJR.07.7081 |url=}}</ref><ref name="pmid7208937">{{cite journal |vauthors=Kundel HL |title=Predictive value and threshold detectability of lung tumors |journal=Radiology |volume=139 |issue=1 |pages=25–9 |year=1981 |pmid=7208937 |doi=10.1148/radiology.139.1.7208937 |url=}}</ref>
Computed tomography is the method of choice for the diagnosis of non-small cell lung cancer.<ref name="pmid8190965">{{cite journal |vauthors=Rosado-de-Christenson ML, Templeton PA, Moran CA |title=Bronchogenic carcinoma: radiologic-pathologic correlation |journal=Radiographics |volume=14 |issue=2 |pages=429–46; quiz 447–8 |year=1994 |pmid=8190965 |doi=10.1148/radiographics.14.2.8190965 |url=}}</ref><ref name="pmid19234288">{{cite journal |vauthors=Parker MS, Chasen MH, Paul N |title=Radiologic signs in thoracic imaging: case-based review and self-assessment module |journal=AJR Am J Roentgenol |volume=192 |issue=3 Suppl |pages=S34–48 |year=2009 |pmid=19234288 |doi=10.2214/AJR.07.7081 |url=}}</ref><ref name="pmid7208937">{{cite journal |vauthors=Kundel HL |title=Predictive value and threshold detectability of lung tumors |journal=Radiology |volume=139 |issue=1 |pages=25–9 |year=1981 |pmid=7208937 |doi=10.1148/radiology.139.1.7208937 |url=}}</ref>
*In some cases, non-small cell lung cancers require further evaluation with  [[MRI]]
*In some cases, non-small cell lung cancers require further evaluation with  [[MRI]]
*Common features of CT scan for the diagnosis of non-small cell lung cancer, include:
*Common features of CT scan for the diagnosis of non-small cell lung cancer include:
:*Assessment of the main bronchi
:*Assessment of the main bronchi
:*Evaluation of the entire thorax
:*Evaluation of the entire thorax

Revision as of 21:50, 23 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]

Overview

Computed tomography is the method of choice for the diagnosis of non-small cell lung cancer. On CT, characteristic findings of non-small cell lung cancer include ground-glass opacity, rounded or spiculated mass, local nodal involvement, intraluminar obstruction, and lobar collapse.

CT

Computed tomography is the method of choice for the diagnosis of non-small cell lung cancer.[1][2][3]

  • In some cases, non-small cell lung cancers require further evaluation with MRI
  • Common features of CT scan for the diagnosis of non-small cell lung cancer include:
  • Assessment of the main bronchi
  • Evaluation of the entire thorax
  • Detection of chest wall invasion
  • Assessment of hilar and mediastinal invasion/adenopathy
  • Determination of non-small cell lung cancer staging
  • Precise determination of size and tumor dimensions
  • Detection of liver, bone, adrenal , and brain metastasis

On CT, characteristic findings of non-small cell lung cancer include:[3]

  • Lung adenocarcinomas are typically peripherally located
  • Usually measure <4 cm in diameter, very few show cavitation
  • Perihilar and mediastinal involvement
  • Ground glass opacity (slow growth), usually lesions double the size within a year
  • Subtype of adenocarcinoma
  • Single pulmonary nodule or mass
  • Multicentric or diffuse disease
  • Localized area of parenchymal consolidation
  • Bubble-like areas of low attenuation within the mass are a characteristic finding
  • Hilar and mediastinal lymphadenopathy is uncommon
  • Persistent peripheral consolidation with associated nodules
  • Centrally located within the lung
  • Usually measure larger than 4 cm in diameter
  • Frequent cavitation
  • Commonly cause segmental or lobar lung collapse due to central location
  • Rapid growth
  • Early metastasizes to the mediastinum and brain
  • Large mediastinal nodules/masses
  • Lymph node involvement (frequently subcarinal)
  • Nodular pleural thickening
  • Pleural effusion
  • On CT, signs of non-small cell lung cancer may include:[3][2]
  • Finger in glove sign: the bronchus distal to the obstruction is dilated
  • Crazy-paving sign: appearance of ground-glass opacity with superimposed interlobular septal thickening and intralobular reticular thickening.

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References

  1. Rosado-de-Christenson ML, Templeton PA, Moran CA (1994). "Bronchogenic carcinoma: radiologic-pathologic correlation". Radiographics. 14 (2): 429–46, quiz 447–8. doi:10.1148/radiographics.14.2.8190965. PMID 8190965.
  2. 2.0 2.1 Parker MS, Chasen MH, Paul N (2009). "Radiologic signs in thoracic imaging: case-based review and self-assessment module". AJR Am J Roentgenol. 192 (3 Suppl): S34–48. doi:10.2214/AJR.07.7081. PMID 19234288.
  3. 3.0 3.1 3.2 Kundel HL (1981). "Predictive value and threshold detectability of lung tumors". Radiology. 139 (1): 25–9. doi:10.1148/radiology.139.1.7208937. PMID 7208937.


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