Neurofibroma: Difference between revisions

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Revision as of 14:22, 12 November 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2] Shanshan Cen, M.D. [3]

Synonyms and keywords:

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Neurofibroma

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Treatment

Case Studies

Case #1

References

Template:Nervous tissue tumors

Template:WikiDoc Sources

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 ==Case Studies==
 [[Neurofibroma case study one|Case #1]]
-==Overview==
-'''Neurofibroma''' is a type of [[nerve sheath tumor]]. In contrast to [[schwannoma]]s - another type of [[tumor]] arising from the [[Schwann cell]]s - neurofibromas incorporate all sorts of cells and structural elements in addition to the Schwann cells.<ref> Miller RT. Immunohistochemistry in the differential diagnosis of schwannoma and neurofibroma.  Propath 2004 Oct. http://www.ihcworld.com/_newsletter/2004/2004-10_NF_vs_schwannoma_v1.pdf</ref>
-==Pathophysiology==
-Neurofibromas infiltrate the nerve and splay apart the individual nerve fibers. Although usually [[benign]], Neurofibromas can sometimes degenerate into [[cancer]].
-Single neurofibromas often occur in middle and old age and grow at the margins of the peripheral nerves, displacing the nerve's main body.
-The [[vestibulocochlear nerve|vestibulocochlear (acoustic) nerve]] is the most commonly affected, (see [[acoustic neuroma]]).
-Other [[cranial nerves]] and [[spinal nerves]] are less commonly involved.
-==Diagnosis==
-===Physical Examination===
-====Skin====
-=====Trunk=====
-<gallery>
-Image:Neurofibroma01.jpg|Neurofibroma. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
-Image:Neurofibroma02.jpg|Neurofibroma. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/  With permission from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL>
-</gallery>
-==Treatment==
-[[Surgical]] resection is curative, although tumors are not easily removable if they surround important nerves such as the optic nerve. There is a risk of functional damage due to interference with the [[nerve]].  [[Debulking]] may be helpful.<ref name="pmid12828709">{{cite journal |author=Babovic S, Bite U, Karnes PS, Babovic-Vuksanovic D |title=Liposuction: a less invasive surgical method of debulking plexiform neurofibromas |journal=Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] |volume=29 |issue=7 |pages=785–7 |year=2003 |pmid=12828709 |doi=}}</ref>
 ==References==

Neurofibroma: Difference between revisions

Revision as of 14:22, 12 November 2015

Diagnosis

Treatment

Case Studies

References

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