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{{CMG}}, {{AE}} [[User:zorkun|Cafer Zorkun]], M.D., PhD.
{{CMG}}, {{AE}} [[User:zorkun|Cafer Zorkun]], M.D., PhD.



Revision as of 13:38, 28 September 2012

Nephrocalcinosis
Medullary nephrocalcinosis.
Image courtesy of RadsWiki

Nephrocalcinosis Microchapters

Home

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Nephrocalcinosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Nephrocalcinosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Nephrocalcinosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Nephrocalcinosis

CDC on Nephrocalcinosis

Nephrocalcinosis in the news

Blogs on Nephrocalcinosis

Directions to Hospitals Treating Nephrocalcinosis

Risk calculators and risk factors for Nephrocalcinosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., PhD.

Synonyms and keywords: Albright's calcinosis

Overview

Nephrocalcinosis is a term originally used to describe deposition of calcium salts in the renal parenchyma due to hyperparathyroidism. It is now more commonly used to describe diffuse, fine, renal parenchymal calcification on radiology.[1] During its early stages, nephrocalcinosis is visible on x-ray, and appears as a fine granular mottling over the renal outlines. These outlines eventually come together to form a dense mass.[2]

It is most commonly seen as an incidental finding with medullary sponge kidney on an abdominal x-ray. However, it may be severe enough to cause (as well as be caused by) renal tubular acidosis or even end stage renal failure, due to disruption of the renal tissue by the deposited calcium.

Histological Perspective

It was once known as Albright's calcinosis after Fuller Albright.

Pathophysiology

Stages of nephrocalcinosis

  • Chemical nephrocalcinosis
  • Microscopic nephrocalcinosis
  • Macroscopic nephrocalcinosis

Causes

Causes of cortical nephrocalcinosis

Causes of medullary nephrocalcinosis

Other causes of hypercalcemia (and thus hypercalciuria)

Differential Diagnosis



Diagnostic Findings

Patient #1

Images courtesy of RadsWiki

Patient #2

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References

  1. "Nephrocalcinosis". eMedicine. 2003-09-09. Retrieved 2007-03-10.
  2. "Albright's Nephrocalcinosis". e-radiology. Retrieved 2007-03-10.

External Links

Additional Resources

  • Genitourinary Imaging: Case Review Series - ISBN 0323037143

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