Metabolic syndrome laboratory findings: Difference between revisions

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*  [[Blood glucose]] (fasting, post-prandial) and [[HbA1C]] to assess for [[diabetes]]
*  [[Blood glucose]] (fasting, post-prandial) and [[HbA1C]] to assess for [[diabetes]]
*  Renal function tests like serum [[uric acid]] and urinary microalbumin to look for [[renal dysfunction]]. [[Hyperuricemia]] has been frequently shown to be associated with metabolic syndrome.
*  Renal function tests like serum [[uric acid]] and urinary microalbumin to look for [[renal dysfunction]]. [[Hyperuricemia]] has been frequently shown to be associated with metabolic syndrome.
*  [[Lipid profile]] - [[hypertriglyceridemia]] or low [[HDL]] levels to assess dyslipidemia.
*  [[Lipid profile]] - [[hypertriglyceridemia]] or low [[HDL]] levels to assess dyslipidemia.<ref name="pmid">{{cite journal |vauthors=Huang PL |title=A comprehensive definition for metabolic syndrome |journal= |volume=2 |issue=5-6 |pages=231–7 |year=2009 |pmid= |pmc=2675814 |doi=10.1242/dmm.001180 |url=}}</ref><ref name="pmid">{{cite journal |vauthors=Huang PL |title=A comprehensive definition for metabolic syndrome |journal= |volume=2 |issue=5-6 |pages=231–7 |year=2009 |pmid= |pmc=2675814 |doi=10.1242/dmm.001180 |url=}}</ref>
* [[Thyroid function test]]s - as increased [[thyroid stimulating hormone]] ([[TSH]]) has been linked to a higher [[prevalence]] of metabolic syndrome
* [[Thyroid function test]]s - as increased [[thyroid stimulating hormone]] ([[TSH]]) has been linked to a higher [[prevalence]] of metabolic syndrome
* [[Liver function test]]s  
* [[Liver function test]]s  

Revision as of 14:02, 17 October 2017

Metabolic syndrome Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Priyamvada Singh, M.B.B.S. [2]; Raviteja Guddeti, M.B.B.S. [3]

Overview

The diagnosis of metabolic syndrome is mostly based on physical examination and lab tests. The diagnostic criteria of different international societies also involves consideration of lab tests like lipid profile and fasting blood glucose.

Laboratory Findings

Metabolic syndrome is a proinflammatory and prothrombotic state. Additional biomarkers that are worth measuring while evaluating metabolic syndrome include:

Studies have shown that elevated levels of these proinflammatory and prothrombotic biomarkers are associated with an increased risk for coronary artery disease (CAD) and type II diabetes. Hence measurement of these markers should be considered in the setting of CAD risk assessment.

If PCOS is suspected the following lab tests should be included in the management of metabolic syndrome:

References

  1. 1.0 1.1 Huang PL (2009). "A comprehensive definition for metabolic syndrome". 2 (5–6): 231–7. doi:10.1242/dmm.001180. PMC 2675814.

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