Medulloblastoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

The hallmark of medulloblastoma is morning headache. Other common symptoms of medulloblastoma include recurrent vomiting, listlessness, and frequent falls.

History

  • When evaluating a patient for medulloblastoma, you should take a detailed history of the presenting symptom (duration, onset, progression), a thorough past medical history review, and a review of any other associated symptoms. When obtaining the history focus on symptoms of any associated syndrome such as:[1][2]

Common Symptoms

Symptoms are mainly due to secondary increased intracranial pressure due to blockage of the fourth ventricle and are usually present for 1 to 5 months before diagnosis is made. The child typically becomes listless, with repeated episodes of vomiting, and a morning headache, which may lead to a misdiagnosis of gastrointestinal disease or migraine. Soon, the child will develop a stumbling gait, frequent falls, diplopia, papilledema, and sixth cranial nerve palsy. Positional dizziness

and nystagmus
are also frequent and f

acial sensory loss or motor weakness may be present. Decerebrate attacks appear late in the disease.

Extraneural metastases to the rest of the body is rare, but usually only after craniotomy.

References

  1. Medulloblastoma. Wikipedia(2015) https://en.wikipedia.org/wiki/Medulloblastoma Accessed on September 2015
  2. Medulloblastoma. Radiopaedia(2015) http://radiopaedia.org/articles/medulloblastoma Accessed on September, 28th 2015


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