Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

MRI is the imaging test of choice for the diagnosis of liposarcoma. MRI findings help to differentiate between the different subtypes of liposarcoma and help to assess distant metastasis.

MRI

MRI findings for a well-differentiated liposarcoma include a mass with at least 75% of adipose content with thin irregular septa. ^[1]
Other subtypes show less adipose content.
Thick septa inside the mass is associated with a more malignant prognosis.
For the dedifferentiated subtype, hemorrhage and necrosis may be observed inside the mass.
The typical appearance of a myxoid liposarcoma has a low signal intensity on T1, in contrast with the high intensity signal in well-differentiated liposarcoma due to the high adipose content. ^[2]
The myxoid subtype may be associated with cystic imaging findings in approximately 20% of cases and may appear multilobulated. ^[3]

Myxoid Liposarcoma Large soft tissue mass is noted at the medial posterior portion of the lower part of the left thigh. It has an isointense signal to the adjacent muscles on T1 sequences with an area of high signal intensity which is suppressed by STIR sequences indicating fatty component. It appears intermediate in signal intensity on T2 sequences with intense enhancement post-gadolinium injection.
Image courtesy of Radiopaedia.org

References

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↑ Peterson, Jeffrey J.; Kransdorf, Mark J.; Bancroft, Laura W.; O'Connor, Mary I. (2003). "Malignant fatty tumors: classification, clinical course, imaging appearance and treatment". Skeletal Radiology. 32 (9): 493–503. doi:10.1007/s00256-003-0647-8. ISSN 0364-2348.
↑ M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter |month= ignored (help)
↑ M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter |month= ignored (help)

Template:WikiDoc Sources

[PetersonKransdorf2003-1] Peterson, Jeffrey J.; Kransdorf, Mark J.; Bancroft, Laura W.; O'Connor, Mary I. (2003). "Malignant fatty tumors: classification, clinical course, imaging appearance and treatment". Skeletal Radiology. 32 (9): 493–503. doi:10.1007/s00256-003-0647-8. ISSN 0364-2348.

[2] M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter |month= ignored (help)

[3] M. S. Sung, H. S. Kang, J. S. Suh, J. H. Lee, J. M. Park, J. Y. Kim & H. G. Lee (2000). "Myxoid liposarcoma: appearance at MR imaging with histologic correlation". Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (4): 1007–1019. doi:10.1148/radiographics.20.4.g00jl021007. PMID 10903690. Unknown parameter |month= ignored (help)

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Liposarcoma MRI

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MRI

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