Liposarcoma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

CT Scan

  • Imaging findings of liposarcoma are frequently characteristic.
  • Focal or diffuse areas of fat associated with nonlipomatous components are commonly detected on computed tomographic or magnetic resonance images.
  • The appearance and morphologic relationship between these areas frequently allow identification of the specific histologic subtype of liposarcoma.

CT Findings According to the Liposarcoma Subtype

Subtypes Density Margins Fat Content Lymph Nodes Around the Tumor Calcifications Necrosis
Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDL) Fat Smooth regular > 65% ++ Few/none +
Dedifferentiated liposarcoma (DDL) Mixed Rough irregular 30-60% +++ Few/none ++
Myxoid/round cell liposarcoma (ML/RCL) Mixed Rough irregular 25-50% + Common +++
Pleomorphic liposarcoma (PL) Soft tissue Incomplete irregular 6-25% + Few/none +
Mixed-type liposarcoma Mixed Smooth regular 30-60% ++ Common +
Table adapted from CT Manifestations in Histologic Subtypes of Retroperitoneal Liposarcoma[1]



References

  1. Jing Lu, Qin Qin, Liang-Liang Zhan, Xi Yang, Qing Xu, Jing Yu, Li-Na Dou, Hao Zhang, Yan Yang, Xiao-Chen Chen, Yue-Hua Yang, Hong-Yan Cheng & Xin-Chen Sun (2014). "Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma". Asian Pacific journal of cancer prevention : APJCP. 15 (15): 6041–6046. PMID 25124571.


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