Lactose intolerance historical perspective: Difference between revisions
Jump to navigation
Jump to search
(Created page with "__NOTOC__ {{Lactose intolerance}} {{CMG}} == Historical Perspective == The ancient Greek physician Hippocrates (460-370 B.C.) first noted gastrointestinal upset and skin ...") |
m (Bot: Removing from Primary care) |
||
| (44 intermediate revisions by 6 users not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Lactose intolerance}} | {{Lactose intolerance}} | ||
{{CMG}}; {{AE}} {{MA}} | |||
==Overview== | |||
Lactose intolerance was first discovered by Hippocrate, the ancient Greek physician 2500 years ago. In 1906, Pimmer discovered lactase enzyme in the [[intestine]] of infant dogs, pigs, and rats. The association between the ethnicity and lactose intolerance was discovered in 1966 by Bayless and Rosensweig. In 1978, breath hydrogen test was used by Levitt to diagnose lactose intolerance. | |||
==Historical Perspective== | |||
===Discovery=== | |||
*Lactose intolerance was first discovered by Hippocrate, the ancient Greek physician 2500 years ago.<ref name="pmid4718561" /> | |||
*In 1906, Pimmer was the first scientist to discover lactase enzyme in the [[intestine]] of infant dogs, pigs, and rats. He also found that this enzyme decreased in the adult intestine of these animals.<ref name="pmid4718561">{{cite journal |vauthors=Neale G |title=The geographical incidence of lactase deficiency |journal=Pathol Microbiol (Basel) |volume=39 |issue=3 |pages=238–47 |year=1973 |pmid=4718561 |doi= |url=}}</ref> | |||
*In 1959, Durand and Holzei et al decribed [[Congenital disorder|congenital]] [[lactase]] deficiency<ref name="pmid4718561" /> | |||
*The association between the ethnicity and lactose intolerance was discovered in 1966 by Bayless and Rosensweig and in 1968 by Neale. | |||
*In the early 1970s, lactase-phlorizin hydrolase (LPH) gene [[Mutation|mutations]] were first implicated in the pathogenesis of lactose intolerance.<ref name="pmid11788828">{{cite journal |vauthors=Enattah NS, Sahi T, Savilahti E, Terwilliger JD, Peltonen L, Järvelä I |title=Identification of a variant associated with adult-type hypolactasia |journal=Nat. Genet. |volume=30 |issue=2 |pages=233–7 |year=2002 |pmid=11788828 |doi=10.1038/ng826 |url=}}</ref> | |||
*In 1978, breath hydrogen test was used by Levitt to diagnose lactose intolerance<ref name="pmid25298621">{{cite journal |vauthors=Rana SV, Malik A |title=Hydrogen breath tests in gastrointestinal diseases |journal=Indian J Clin Biochem |volume=29 |issue=4 |pages=398–405 |year=2014 |pmid=25298621 |pmc=4175689 |doi=10.1007/s12291-014-0426-4 |url=}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | |||
{{WH}} | |||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category: | [[Category:Medicine]] | ||
[[Category:Up-To-Date]] | |||
Latest revision as of 22:28, 29 July 2020
|
Lactose Intolerance Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Lactose intolerance historical perspective On the Web |
|
American Roentgen Ray Society Images of Lactose intolerance historical perspective |
|
Risk calculators and risk factors for Lactose intolerance historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
Lactose intolerance was first discovered by Hippocrate, the ancient Greek physician 2500 years ago. In 1906, Pimmer discovered lactase enzyme in the intestine of infant dogs, pigs, and rats. The association between the ethnicity and lactose intolerance was discovered in 1966 by Bayless and Rosensweig. In 1978, breath hydrogen test was used by Levitt to diagnose lactose intolerance.
Historical Perspective
Discovery
- Lactose intolerance was first discovered by Hippocrate, the ancient Greek physician 2500 years ago.[1]
- In 1906, Pimmer was the first scientist to discover lactase enzyme in the intestine of infant dogs, pigs, and rats. He also found that this enzyme decreased in the adult intestine of these animals.[1]
- In 1959, Durand and Holzei et al decribed congenital lactase deficiency[1]
- The association between the ethnicity and lactose intolerance was discovered in 1966 by Bayless and Rosensweig and in 1968 by Neale.
- In the early 1970s, lactase-phlorizin hydrolase (LPH) gene mutations were first implicated in the pathogenesis of lactose intolerance.[2]
- In 1978, breath hydrogen test was used by Levitt to diagnose lactose intolerance[3]
References
- ↑ 1.0 1.1 1.2 Neale G (1973). "The geographical incidence of lactase deficiency". Pathol Microbiol (Basel). 39 (3): 238–47. PMID 4718561.
- ↑ Enattah NS, Sahi T, Savilahti E, Terwilliger JD, Peltonen L, Järvelä I (2002). "Identification of a variant associated with adult-type hypolactasia". Nat. Genet. 30 (2): 233–7. doi:10.1038/ng826. PMID 11788828.
- ↑ Rana SV, Malik A (2014). "Hydrogen breath tests in gastrointestinal diseases". Indian J Clin Biochem. 29 (4): 398–405. doi:10.1007/s12291-014-0426-4. PMC 4175689. PMID 25298621.