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{{SK}} Olfactogenital dysplasia; de Morsier-Gauthier syndrome
{{SK}} Olfactogenital dysplasia; de Morsier-Gauthier syndrome
==Treatment==
Treatment is directed at restoring the deficient hormones -- known as [[hormone therapy]] (HT). Males are administered [[human chorionic gonadotropin]] (hCG) or [[testosterone]]. Females are treated with [[Estrogen|oestrogen]] and [[progestin]]s. 
To induce fertility in males or females, GnRH (aka LHRH) is administered by an [[infusion pump]], or hCG/hMG/FSH/LH combinations are administered through regular injections. Fertility is only maintained whilst actually being treated with these hormones.  Once fertility treatment stops it is necessary to revert to the normal HRT of testosterone for men and oestrogen + progestins for women.
The main health risk, for both men and women, of untreated Kallmann Syndrome is [[osteoporosis]]. Therefore, regular bone density scans (every 2 years or so) are advisable, even if being treated with HRT. Additional medication specifically for osteoporosis is necessary in some cases.
== Psychological Issues ==
== Psychological Issues ==
In some cases, the psychological effects of having this condition can outweigh the significance of any physical symptoms.
In some cases, the psychological effects of having this condition can outweigh the significance of any physical symptoms.

Revision as of 16:36, 19 September 2012

Kallman syndrome
The structure of GNRH1
(from PDB: 1YY1​)
ICD-10 E23.0
ICD-9 253.4
OMIM 308700 147950 244200 138850 607002
DiseasesDB 7091
MeSH D017436

Kallman syndrome Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Olfactogenital dysplasia; de Morsier-Gauthier syndrome

Psychological Issues

In some cases, the psychological effects of having this condition can outweigh the significance of any physical symptoms.

The social stigma of being left behind by your peer group at a vital stage of physical and emotional development can leave lasting damage to some people. Some people with Kallmann syndrome find it difficult to fit into social groups and may have trouble in forming relationships both on the physical and emotional level. This might be more profound in people who are diagnosed later in life.

Practical Issues

While the lack of sense of smell may not be important when compared to the lack of sexual development, it does give rise to a few situations where care should be taken. These can include:

Personal hygiene.

Gas leaks within the home. Fitting gas detectors within the home is recommended.

Food & drink spoilage. Extra care should be taken with the expiration dates for food and drink.

References


External links

Template:Skin and subcutaneous tissue symptoms and signs Template:Nervous and musculoskeletal system symptoms and signs Template:Urinary system symptoms and signs Template:Cognition, perception, emotional state and behaviour symptoms and signs Template:Speech and voice symptoms and signs Template:General symptoms and signs

de:Kallmann-Syndrom it:Sindrome di Kallmann he:תסמונת קלמן nl:Syndroom van Kallmann fi:Kallmannin oireyhtymä


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