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==Overview==
==Overview==
Less than 1% of people infected with Japanese encephalitis (JE) virus develop clinical illness. Mild infections occur without apparent symptoms other than [[fever]] with [[headache]]. More severe infection is marked by quick onset, [[headache]], high [[fever]], neck stiffness, stupor, disorientation, [[coma]], [[tremors]], occasional [[convulsions]] (especially in infants) and spastic (but rarely flaccid) [[paralysis]].
Most patients infected with Japanese encephalitis remain [[asymptomatic]]; 1% of infected individuals develop clinical disease. The [[incubation period]] for Japanese encephalitis is usually 5-15 days. Common symptoms of Japanese encephalitis include [[fever]], [[headache]], and [[vomiting]].


==Common Symptoms==
==History and Symptoms==
The incubation period for Japanese encephalitis is usually from 5 to 15 days.
===History and Symptoms===
*In persons who develop symptoms, the [[incubation period]] (time from infection until illness) is typically 5-15 days.
If possible, a detailed and thorough history from the patient is necessary. Most patients infected with Japanese encephalitis remain [[asymptomatic]]; 1% of infected individuals develop clinical disease. The [[incubation period]] for Japanese encephalitis is usually 5-15 days. Common symptoms of Japanese encephalitis include:<ref name=Mandell1> M.D. JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Expert Consult Premium Edition. Saunders; 2014.</ref><ref name=CDCClinical> Japanese Encephalitis, Clinical and Laboratory Evaluation. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/japaneseencephalitis/healthcareproviders/healthcareproviders-clinlabeval.html Accessed on April 14, 2016. </ref><ref name="pmid23235298">{{cite journal| author=Centers for Disease Control and Prevention (CDC)| title=Expanding poliomyelitis and measles surveillance networks to establish surveillance for acute meningitis and encephalitis syndromes--Bangladesh, China, and India, 2006-2008. | journal=MMWR Morb Mortal Wkly Rep | year= 2012 | volume= 61 | issue= 49 | pages= 1008-11 | pmid=23235298 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23235298  }} </ref><ref name="pmid27050192">{{cite journal| author=Chansamouth V, Thammasack S, Phetsouvanh R, Keoluangkot V, Moore CE, Blacksell SD et al.| title=The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos. | journal=PLoS Negl Trop Dis | year= 2016 | volume= 10 | issue= 4 | pages= e0004577 | pmid=27050192 | doi=10.1371/journal.pntd.0004577 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27050192  }} </ref>
*Initial symptoms often include [[fever]], [[headache]], and [[vomiting]].
*[[Fever]]
*Mental status changes, [[neurologic]] symptoms, weakness, and movement disorders might develop over the next few days.
*[[Chills]]
*[[Seizure]]s are common, especially among children.
*[[Headache]]
*More severe infection is marked by quick onset, [[headache]], high fever, neck stiffness, stupor, disorientation, [[coma]], [[tremors]], occasional convulsions (especially in infants) and spastic (but rarely flaccid) paralysis.
*[[Fatigue]]
*[[myalgia|Muscle pain]]
*[[Dizziness]]
*[[Altered mental status]]
*[[Vomiting]]
*[[Weakness]]
*[[Neck stiffness]]


==References==
==References==
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{{Reflist|2}}
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[[Category:Neurology]]
 
 
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Latest revision as of 18:06, 18 September 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]

Overview

Most patients infected with Japanese encephalitis remain asymptomatic; 1% of infected individuals develop clinical disease. The incubation period for Japanese encephalitis is usually 5-15 days. Common symptoms of Japanese encephalitis include fever, headache, and vomiting.

History and Symptoms

History and Symptoms

If possible, a detailed and thorough history from the patient is necessary. Most patients infected with Japanese encephalitis remain asymptomatic; 1% of infected individuals develop clinical disease. The incubation period for Japanese encephalitis is usually 5-15 days. Common symptoms of Japanese encephalitis include:[1][2][3][4]

References

  1. M.D. JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Expert Consult Premium Edition. Saunders; 2014.
  2. Japanese Encephalitis, Clinical and Laboratory Evaluation. Centers for Disease Control and Prevention (2015). http://www.cdc.gov/japaneseencephalitis/healthcareproviders/healthcareproviders-clinlabeval.html Accessed on April 14, 2016.
  3. Centers for Disease Control and Prevention (CDC) (2012). "Expanding poliomyelitis and measles surveillance networks to establish surveillance for acute meningitis and encephalitis syndromes--Bangladesh, China, and India, 2006-2008". MMWR Morb Mortal Wkly Rep. 61 (49): 1008–11. PMID 23235298.
  4. Chansamouth V, Thammasack S, Phetsouvanh R, Keoluangkot V, Moore CE, Blacksell SD; et al. (2016). "The Aetiologies and Impact of Fever in Pregnant Inpatients in Vientiane, Laos". PLoS Negl Trop Dis. 10 (4): e0004577. doi:10.1371/journal.pntd.0004577. PMID 27050192.


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