Japanese encephalitis historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anthony Gallo, B.S. [2]

Overview

Japanese encephalitis was first discovered in 1871 following a large number of recurring outbreaks in the summer months. In 1930, the first vaccine was developed to prevent Japanese encephalitis; today, there are approximately 15 vaccines available.

Historical Perspective

Japanese encephalitis was first discovered in 1871 following a large number of recurring outbreaks in the summer months. There have been several outbreaks of Japanese encephalitis, which occurred in 1927, 1934, and 1935.[1] The association between Culex tritaeniorhynchus as a vector and the involvement of birds and pigs as reservoir hosts for Japanese encephalitis was made in 1938.[2] In 1930, the first vaccine was developed to prevent Japanese encephalitis; today, there are approximately 15 vaccines available.[3]

References

  1. Erlanger TE, Weiss S, Keiser J, Utzinger J, Wiedenmayer K (2009). "Past, present, and future of Japanese encephalitis". Emerg Infect Dis. 15 (1): 1–7. doi:10.3201/eid1501.080311. PMC 2660690. PMID 19116041.
  2. Tsai TF, Yu, XY. 1994 Japanese encephalitis vaccines. Plotkin SA, Mortimer EA, eds. Vaccines. Second edition. Philadel- pha: W. B. Saunders, 671–714.
  3. Paulke-Korinek M, Kollaritsch H (2008). "Japanese encephalitis and vaccines: past and future prospects". Wien Klin Wochenschr. 120 (19-20 Suppl 4): 15–9. doi:10.1007/s00508-008-1071-9. PMID 19066766.


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