Interstitial nephritis history and symptoms: Difference between revisions

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{{Interstitial nephritis}}
{{Interstitial nephritis}}
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==Overview==
 
==History and Symptoms==
==History and Symptoms==
At times there are no symptoms of this disease, but when they do occur they are widely varied and can occur rapidly or gradually<ref name="pmid11473672">{{cite journal |author=Rossert J |title=Drug-induced acute interstitial nephritis |journal=Kidney Int |volume=60 |issue=2 |pages=804-17 |year=2001 |pmid=11473672 | url=http://www.nature.com/ki/journal/v60/n2/full/4492487a.html | doi=10.1046/j.1523-1755.2001.060002804.x}}</ref><ref name="pmid14671029">.</ref><ref name="pmid6604293">{{cite journal |author=Pusey C, Saltissi D, Bloodworth L, Rainford D, Christie J |title=Drug associated acute interstitial nephritis: clinical and pathological features and the response to high dose steroid therapy |journal=Q J Med |volume=52 |issue=206 |pages=194-211 |year=1983 |pmid=6604293}}</ref><ref name="pmid3779558">{{cite journal |author=Handa S |title=Drug-induced acute interstitial nephritis: report of 10 cases |journal=CMAJ |volume=135 |issue=11 |pages=1278-81 |year=1986 |pmid=3779558}}</ref><ref name="pmid2113219">{{cite journal |author=Buysen J, Houthoff H, Krediet R, Arisz L |title=Acute interstitial nephritis: a clinical and morphological study in 27 patients |journal=Nephrol Dial Transplant |volume=5 |issue=2 |pages=94-9 |year=1990 |pmid=2113219}}</ref>.  When caused by an allergic reaction, the symptoms of acute tubulointerstitial nephritis are fever (27% of patients)<ref name="pmid14671029">.</ref>, rash (15% of patients)<ref name="pmid14671029">.</ref>, and enlarged kidneys.  Some people experience [[dysuria]], and lower back pain.  In chronic tubulointerstitial nephritis the patient can experience symptoms such as nausea, vomiting, fatigue, and weight loss.  Other conditions that may develop include [[hyperkalemia]], [[metabolic acidosis]], and kidney failure.  
At times there are no symptoms of this disease, but when they do occur they are widely varied and can occur rapidly or gradually<ref name="pmid11473672">{{cite journal |author=Rossert J |title=Drug-induced acute interstitial nephritis |journal=Kidney Int |volume=60 |issue=2 |pages=804-17 |year=2001 |pmid=11473672 | url=http://www.nature.com/ki/journal/v60/n2/full/4492487a.html | doi=10.1046/j.1523-1755.2001.060002804.x}}</ref><ref name="pmid14671029">.</ref><ref name="pmid6604293">{{cite journal |author=Pusey C, Saltissi D, Bloodworth L, Rainford D, Christie J |title=Drug associated acute interstitial nephritis: clinical and pathological features and the response to high dose steroid therapy |journal=Q J Med |volume=52 |issue=206 |pages=194-211 |year=1983 |pmid=6604293}}</ref><ref name="pmid3779558">{{cite journal |author=Handa S |title=Drug-induced acute interstitial nephritis: report of 10 cases |journal=CMAJ |volume=135 |issue=11 |pages=1278-81 |year=1986 |pmid=3779558}}</ref><ref name="pmid2113219">{{cite journal |author=Buysen J, Houthoff H, Krediet R, Arisz L |title=Acute interstitial nephritis: a clinical and morphological study in 27 patients |journal=Nephrol Dial Transplant |volume=5 |issue=2 |pages=94-9 |year=1990 |pmid=2113219}}</ref>.  When caused by an allergic reaction, the symptoms of acute tubulointerstitial nephritis are fever (27% of patients)<ref name="pmid14671029">.</ref>, rash (15% of patients)<ref name="pmid14671029">.</ref>, and enlarged kidneys.  Some people experience [[dysuria]], and lower back pain.  In chronic tubulointerstitial nephritis the patient can experience symptoms such as nausea, vomiting, fatigue, and weight loss.  Other conditions that may develop include [[hyperkalemia]], [[metabolic acidosis]], and kidney failure.  
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[[Category:Kidney diseases]]

Revision as of 18:42, 13 February 2013

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

History and Symptoms

At times there are no symptoms of this disease, but when they do occur they are widely varied and can occur rapidly or gradually[1][2][3][4][5]. When caused by an allergic reaction, the symptoms of acute tubulointerstitial nephritis are fever (27% of patients)[2], rash (15% of patients)[2], and enlarged kidneys. Some people experience dysuria, and lower back pain. In chronic tubulointerstitial nephritis the patient can experience symptoms such as nausea, vomiting, fatigue, and weight loss. Other conditions that may develop include hyperkalemia, metabolic acidosis, and kidney failure.

References

  1. Rossert J (2001). "Drug-induced acute interstitial nephritis". Kidney Int. 60 (2): 804–17. doi:10.1046/j.1523-1755.2001.060002804.x. PMID 11473672.
  2. 2.0 2.1 2.2 .
  3. Pusey C, Saltissi D, Bloodworth L, Rainford D, Christie J (1983). "Drug associated acute interstitial nephritis: clinical and pathological features and the response to high dose steroid therapy". Q J Med. 52 (206): 194–211. PMID 6604293.
  4. Handa S (1986). "Drug-induced acute interstitial nephritis: report of 10 cases". CMAJ. 135 (11): 1278–81. PMID 3779558.
  5. Buysen J, Houthoff H, Krediet R, Arisz L (1990). "Acute interstitial nephritis: a clinical and morphological study in 27 patients". Nephrol Dial Transplant. 5 (2): 94–9. PMID 2113219.

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