Hyperparathyroidism x ray: Difference between revisions

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{{Hyperparathyroidism}}
{{Hyperparathyroidism}}
{{CMG}}; {{AE}} {{Anmol}}


==Overview==
==Overview==
X-ray is helpful in diagnosis of hyperparathyroidism. Finding in primary hyperparathyroidism includes subperiosteal [[bone resorption]], endoosteal [[bone resorption]], subchondral [[resorption]], subligamentous [[resorption]], intracortical [[resorption]], [[osteopenia]], [[Brown tumor|brown tumors]], salt and pepper sign in the skull (pepper pot skull), and [[chondrocalcinosis]]. X-ray is the preferred imaging for diagnosis of secondary hyperparathyroidism as majority of findings are radiological. Findings in secondary and tertiary hyperparathyroidism are often associated with the [[osteosclerosis]] of renal [[osteodystrophy]], and the [[osteomalacia]] of [[vitamin D deficiency]] and includes subperiosteal [[bone resorption]],subchondral resorption, subligamentous resorption, severe [[osteopenia]], [[osteosclerosis]], [[brown tumor]], [[amyloid]] deposition, soft tissue and vascular [[calcification]], superior and inferior rib notching, and [[osteonecrosis]].
==X Ray==
==X Ray==
===Primary hyperparathyroidism===
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Finding in primary hyperparathyroidism includes:<ref name="pmid24614783">{{cite journal |vauthors=Lachungpa T, Sarawagi R, Chakkalakkoombil SV, Jayamohan AE |title=Imaging features of primary hyperparathyroidism |journal=BMJ Case Rep |volume=2014 |issue= |pages= |year=2014 |pmid=24614783 |pmc=3962932 |doi=10.1136/bcr-2013-203521 |url=}}</ref>
Finding in primary hyperparathyroidism includes:<ref name="pmid24614783">{{cite journal |vauthors=Lachungpa T, Sarawagi R, Chakkalakkoombil SV, Jayamohan AE |title=Imaging features of primary hyperparathyroidism |journal=BMJ Case Rep |volume=2014 |issue= |pages= |year=2014 |pmid=24614783 |pmc=3962932 |doi=10.1136/bcr-2013-203521 |url=}}</ref>
*Subperiosteal bone resorption
*Subperiosteal [[bone resorption]]
**Classically affects the radial aspects of the proximal and middle phalanges of the 2nd and 3rd fingers
**Classically affects the radial aspects of the proximal and middle [[phalanges]] of the index and middle fingers
**Medial aspect of tibia, femur, humerus
**Medial aspect of [[tibia]], [[femur]], [[humerus]]
**Phalyngeal tuft erosion (acro-osteolysis)
**Phalangeal tuft erosion (acro-osteolysis)
**Lamina dura around teeth (floating teeth)
**Lamina dura around teeth (floating teeth)
*Endoosteal bone resorption
*Endoosteal [[bone resorption]]
**Widening of medullary cavity
**Widening of [[medullary cavity]]
**Thinning of the inner cortex
**Thinning of the inner [[cortex]]
*Subchondral resorption
*Subchondral [[resorption]]
**Lateral end of the clavicles
**Lateral end of the [[Clavicle|clavicles]]
**Symphysis pubis
**[[Pubic symphysis|Symphysis pubis]]
**Sacroiliac joints
**[[Sacroiliac joint|Sacroiliac joints]]
*Subligamentous resorption
*Subligamentous [[resorption]]
**Ischial tuberosity
**[[Ischial tuberosity]]
**Humeral tuberosity
**Humeral tuberosity
**Trochanters
**[[Trochanters]]
**Inferior surface of calcaneus
**Inferior surface of [[calcaneus]]
**Inferior margin of lateral clavicle
**Inferior margin of lateral [[clavicle]]
*Intracortical resorption: cigar/oval-shaped or tunnel-shaped radiolucency in the cortex
*Intracortical [[resorption]]: cigar/oval-shaped or tunnel-shaped radiolucency in the cortex
*Osteopaenia
*[[Osteopenia]]
*Brown tumours
*[[Brown tumor|Brown tumors]]
*Salt and pepper sign in the skull (pepper pot skull)
*Salt and pepper sign in the skull (pepper pot skull)
*Chondrocalcinosis
*[[Chondrocalcinosis]]


X-ray is the preferred imaging for diagnosis of secondary hyperparathyroidism as majority of findings are radiological. <ref name="pmid7785573">{{cite journal |vauthors=Tigges S, Nance EP, Carpenter WA, Erb R |title=Renal osteodystrophy: imaging findings that mimic those of other diseases |journal=AJR Am J Roentgenol |volume=165 |issue=1 |pages=143–8 |year=1995 |pmid=7785573 |doi=10.2214/ajr.165.1.7785573 |url=http://www.ajronline.org/doi/pdf/10.2214/ajr.165.1.7785573}}</ref>
===Secondary and tertiary hyperparathyroidism===
Findings in secondary and tertiary hyperparathyroidism are often associated with the osteosclerosis of renal osteodystrophy, and the osteomalacia of vitamin D deficiency:
X-ray is the preferred imaging for diagnosis of secondary hyperparathyroidism as majority of findings are radiological. <ref name="pmid7785573">{{cite journal |vauthors=Tigges S, Nance EP, Carpenter WA, Erb R |title=Renal osteodystrophy: imaging findings that mimic those of other diseases |journal=AJR Am J Roentgenol |volume=165 |issue=1 |pages=143–8 |year=1995 |pmid=7785573 |doi=10.2214/ajr.165.1.7785573 |url=http://www.ajronline.org/doi/pdf/10.2214/ajr.165.1.7785573}}</ref> Findings in secondary and tertiary hyperparathyroidism are often associated with the [[osteosclerosis]] of renal [[osteodystrophy]], and the [[osteomalacia]] of [[vitamin D deficiency]]:
*Subperiosteal bone resorption
*Subperiosteal [[bone resorption]]
**Radial aspect of middle phalanges of index and long fingers are involved.
**Radial aspect of middle [[phalanges]] of index and long fingers are involved.
*Subchondral resorption
*Subchondral resorption
**Hands, hips, shoulders, patellofemoral and sacroiliac joints are involved.
**[[Hands]], [[hips]], [[shoulders]], patellofemoral and [[Sacroiliac joint|sacroiliac joints]] are involved.
**Hands are involves in the ulnar side.
**Hands are involves in the [[ulnar]] side.
**Distal interphalangeal and metacarpophalangeal joints are involved.
**Distal [[interphalangeal]] and [[metacarpophalangeal]] joints are involved.
**Subchondral resorption is very severe. It may lead to bony collapse.
**Subchondral [[resorption]] is very severe. It may lead to bony collapse.
*Subligamentous resorption
*Subligamentous resorption
**Retrocalcaneal bursa and insertion of planter aponeurosis may be involved.
**Retrocalcaneal bursa and insertion of planter [[aponeurosis]] may be involved.
*Severe osteopenia, may be complicated by pathologic fractures
*Severe [[osteopenia]], may be complicated by pathologic fractures
*Osteosclerosis, e.g. rugger-jersey spine
*[[Osteosclerosis]], e.g. rugger-jersey spine
*Brown tumor
*[[Brown tumor]]
*Amyloid deposition
*[[Amyloid]] deposition
**May be manifested as lytic bone lesion on radiograph
**May be manifested as lytic bone lesion on radiograph
*Soft tissue and vascular calcification
*Soft tissue and vascular [[calcification]]
*Superior and inferior rib notching
*Superior and inferior rib notching
*Osteonecrosis may be often observed in patients in whom steroid is administered for prevention of renal transplant rejection.
*[[Osteonecrosis]] may be often observed in patients in whom [[steroid]] is administered for prevention of [[Kidney transplantation|renal transplant]] rejection.
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[[image:Subperiosteal bone resorption.gif|thumb|600px|Subperiosteal bone resorption - [https://radiopaedia.org/articles/subperiosteal-bone-resorption Source:Radiopedia]]]
[[image:Subperiosteal bone resorption.gif|thumb|500px|Subperiosteal bone resorption - [https://radiopaedia.org/articles/subperiosteal-bone-resorption Source:Radiopedia]]]
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[[image:Brown tumor.gif|thumb|600px|Brown tumors - [https://radiopaedia.org/cases/renal-osteodystrophy-and-brown-tumours-1 Source:Case courtesy of A.Prof Frank Gaillard, Radiopedia]]]
[[image:Brown tumor.gif|thumb|500px|Brown tumors - [https://radiopaedia.org/cases/renal-osteodystrophy-and-brown-tumours-1 Source:Case courtesy of A.Prof Frank Gaillard, Radiopedia]]]
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[[image:Salt-and-pepper-sign-skull compared to normal skull.png|thumb|600px|Normal skull compared to Salt & pepper appearance of skull - [https://radiopaedia.org/cases/21127 Source:Radiopedia]]]
[[image:Salt-and-pepper-sign-skull compared to normal skull.png|thumb|500px|Normal skull compared to Salt & pepper appearance of skull - [https://radiopaedia.org/cases/21127 Source:Radiopedia]]]
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[[image:Acro-osteolytis.gif|thumb|600px|Acro-osteolytis, terminal tufts erosion - [https://radiopaedia.org/cases/9738 Source:Case courtesy of Dr Andrew Dixon, Radiopedia]]]
[[image:Acro-osteolytis.gif|thumb|500px|Acro-osteolytis, terminal tufts erosion - [https://radiopaedia.org/cases/9738 Source:Case courtesy of Dr Andrew Dixon, Radiopedia]]]
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{{Reflist|2}}
{{Reflist|2}}
[[Category:Disease]]
[[Category:Medicine]]
[[Category:Endocrinology]]
[[Category:Parathyroid disorders]]
[[Category:Parathyroid disorders]]
[[Category:Endocrinology]]
[[Category:Up-To-Date]]
[[Category:Radiology]]

Latest revision as of 22:17, 29 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]

Overview

X-ray is helpful in diagnosis of hyperparathyroidism. Finding in primary hyperparathyroidism includes subperiosteal bone resorption, endoosteal bone resorption, subchondral resorption, subligamentous resorption, intracortical resorption, osteopenia, brown tumors, salt and pepper sign in the skull (pepper pot skull), and chondrocalcinosis. X-ray is the preferred imaging for diagnosis of secondary hyperparathyroidism as majority of findings are radiological. Findings in secondary and tertiary hyperparathyroidism are often associated with the osteosclerosis of renal osteodystrophy, and the osteomalacia of vitamin D deficiency and includes subperiosteal bone resorption,subchondral resorption, subligamentous resorption, severe osteopenia, osteosclerosis, brown tumor, amyloid deposition, soft tissue and vascular calcification, superior and inferior rib notching, and osteonecrosis.

X Ray

Primary hyperparathyroidism

Finding in primary hyperparathyroidism includes:[1]

Secondary and tertiary hyperparathyroidism

X-ray is the preferred imaging for diagnosis of secondary hyperparathyroidism as majority of findings are radiological. [2] Findings in secondary and tertiary hyperparathyroidism are often associated with the osteosclerosis of renal osteodystrophy, and the osteomalacia of vitamin D deficiency:

Subperiosteal bone resorption - Source:Radiopedia
Brown tumors - Source:Case courtesy of A.Prof Frank Gaillard, Radiopedia
Normal skull compared to Salt & pepper appearance of skull - Source:Radiopedia
Acro-osteolytis, terminal tufts erosion - Source:Case courtesy of Dr Andrew Dixon, Radiopedia

References

  1. Lachungpa T, Sarawagi R, Chakkalakkoombil SV, Jayamohan AE (2014). "Imaging features of primary hyperparathyroidism". BMJ Case Rep. 2014. doi:10.1136/bcr-2013-203521. PMC 3962932. PMID 24614783.
  2. Tigges S, Nance EP, Carpenter WA, Erb R (1995). "Renal osteodystrophy: imaging findings that mimic those of other diseases". AJR Am J Roentgenol. 165 (1): 143–8. doi:10.2214/ajr.165.1.7785573. PMID 7785573.