Hyperparathyroidism classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]
Overview
Hyperparathyroidism can be classified according to origin of defect into primary, secondary and tertiary.
Classification
Hyperparathyroidism can be classified according to origin of defect into primary, secondary and tertiary.
Primary hyperparathyroidism
- Primary hyperparathyroidism is due to over activity of the parathyroid glands themselves. The most important causes of oversecretion of parathyroid hormone include:
- Adenoma
- Hyperplasia
- Carcinoma of the parathyroid glands
Secondary hyperparathyroidism
Secondary hyperparathyroidism is due to increase in secretion of parathyroid hormone from a secondary process.
Tertiary hyperparathyroidism
Tertiary hyperparathyroidism is a state of excessive secretion of parathyroid hormone (PTH) after a long period of secondary hyperparathyroidism and resulting in hypercalcemia even after treatment of secondary hyperparathyroidism.
| Hyperparathyroidism | |||||||||||||||||||||||||||||||||||||
| Primary hyperparathyroidism | Secondary hyperparathyroidism | Tertiary hyperparathyroidosm | |||||||||||||||||||||||||||||||||||
| •Parathyroid adenoma •Parathyroid hyperplasia •Parathyroid carcinoma | •Chronic renal failure •Vitamin D deficiency | •Post-renal transplantation | |||||||||||||||||||||||||||||||||||