Hereditary nonpolyposis colorectal cancer risk factors: Difference between revisions
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==Risk Factors== | ==Risk Factors== | ||
=== | *The most potent risk factor in the development of hereditary nonpolyposis colorectal cancer is gene mutations caused by defective DNA mismatch repair.<ref name="pmid26474631">{{cite journal |vauthors=Si JW, Wang L, Ba XJ, Zhang X, Dong Y, Zhang JX, Li WT, Li T |title=[Clinicopathological screening of Lynch syndrome: a report of 2 cases and literature review] |language=Chinese |journal=Beijing Da Xue Xue Bao |volume=47 |issue=5 |pages=858–64 |year=2015 |pmid=26474631 |doi= |url=}}</ref> | ||
*The | *The main genes associated with high risk of developing hereditary nonpolyposis colorectal cancer, include:<ref name="pmid26474631">{{cite journal |vauthors=Si JW, Wang L, Ba XJ, Zhang X, Dong Y, Zhang JX, Li WT, Li T |title=[Clinicopathological screening of Lynch syndrome: a report of 2 cases and literature review] |language=Chinese |journal=Beijing Da Xue Xue Bao |volume=47 |issue=5 |pages=858–64 |year=2015 |pmid=26474631 |doi= |url=}}</ref> | ||
:*MLH1 | |||
:*MSH2 | |||
:*MSH6 | |||
* | :*PMS2 | ||
* | * To learn more about hereditary nonpolyposis colorectal cancer genetic mutations [[Hereditary nonpolyposis colorectal cancer pathophysiology|click here]] | ||
==References== | ==References== |
Revision as of 20:14, 9 February 2016
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Overview
The most potent risk factor in the development of hereditary nonpolyposis colorectal cancer is gene mutations caused by defective DNA mismatch repair.[1]
Risk Factors
- The most potent risk factor in the development of hereditary nonpolyposis colorectal cancer is gene mutations caused by defective DNA mismatch repair.[1]
- The main genes associated with high risk of developing hereditary nonpolyposis colorectal cancer, include:[1]
- MLH1
- MSH2
- MSH6
- PMS2
- To learn more about hereditary nonpolyposis colorectal cancer genetic mutations click here