Hereditary nonpolyposis colorectal cancer risk factors: Difference between revisions
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{{Hereditary nonpolyposis colorectal cancer}} | {{Hereditary nonpolyposis colorectal cancer}} | ||
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==Overview== | ==Overview== | ||
The most potent risk factor in the development of hereditary nonpolyposis colorectal cancer is gene mutations caused by defective DNA mismatch repair. | The most [[Potency|potent]] [[risk factor]] in the development of hereditary nonpolyposis colorectal cancer is [[gene]] [[Mutation|mutations]] caused by defective [[DNA mismatch repair]]. | ||
==Risk Factors== | ==Risk Factors== | ||
=== | *The most [[Potency|potent]] [[risk factor]] in the development of hereditary nonpolyposis colorectal cancer is [[gene]] [[Mutation|mutations]] caused by defective [[DNA mismatch repair]].<ref name="pmid26474631">{{cite journal |vauthors=Si JW, Wang L, Ba XJ, Zhang X, Dong Y, Zhang JX, Li WT, Li T |title=[Clinicopathological screening of Lynch syndrome: a report of 2 cases and literature review] |language=Chinese |journal=Beijing Da Xue Xue Bao |volume=47 |issue=5 |pages=858–64 |year=2015 |pmid=26474631 |doi= |url=}}</ref> | ||
* | *[[Gene|Genes]] associated with high risk of developing hereditary nonpolyposis colorectal cancer include:<ref name="pmid26474631">{{cite journal |vauthors=Si JW, Wang L, Ba XJ, Zhang X, Dong Y, Zhang JX, Li WT, Li T |title=[Clinicopathological screening of Lynch syndrome: a report of 2 cases and literature review] |language=Chinese |journal=Beijing Da Xue Xue Bao |volume=47 |issue=5 |pages=858–64 |year=2015 |pmid=26474631 |doi= |url=}}</ref> | ||
:*[[MLH1]] | |||
:*[[MSH2]] | |||
:*[[MSH6]] | |||
* | :*[[PMS2]] | ||
* | * To learn more about hereditary nonpolyposis colorectal cancer [[Mutation|genetic mutations]], [[Hereditary nonpolyposis colorectal cancer pathophysiology|click here]] | ||
* | |||
==References== | ==References== | ||
{{reflist| | {{reflist|1}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
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Latest revision as of 18:39, 29 April 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]Ali Akram, M.B.B.S.[3]
Overview
The most potent risk factor in the development of hereditary nonpolyposis colorectal cancer is gene mutations caused by defective DNA mismatch repair.
Risk Factors
- The most potent risk factor in the development of hereditary nonpolyposis colorectal cancer is gene mutations caused by defective DNA mismatch repair.[1]
- Genes associated with high risk of developing hereditary nonpolyposis colorectal cancer include:[1]
- To learn more about hereditary nonpolyposis colorectal cancer genetic mutations, click here